نتائج البحث

1

Rational approach to drug discovery for human schistosomiasis

المؤلفون: Stanton F. McHardy, Jayce Rhodes, Philip T. LoVerde, Sevan N. Alwan, Alexander B. Taylor, Frédéric D. Chevalier, Tim J. Anderson

المصدر: International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss, Pp 140-147 (2021)
International Journal for Parasitology: Drugs and Drug Resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ad22ea34eec634b1281c48442ebaebTest
http://www.sciencedirect.com/science/article/pii/S221132072100021XTest

2

Effects of iron chelating agent on Schistosoma mansoni infected murine model

المؤلفون: Manal Z. M. Abdellatif, Ekhlas H. Abdel-Hafeez, Usama S. Belal, Rabie M. Mohamed, Abdel-Razik H. Abdel-Razik, Kamel M.A. Hassanin, Ahmed Abdel-Wahab, Noha H. Abdelgelil

المصدر: Biomedicine & Pharmacotherapy, Vol 109, Iss, Pp 28-38 (2019)

مصطلحات موضوعية: 0301 basic medicine, Liver Cirrhosis, Male, Histopathology, Schistosomiasis, Heme, RM1-950, Deferoxamine, Iron Chelating Agents, Iron chelation (deferoxamine), Excretion, Andrology, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, Interferon gamma, Pharmacology, chemistry.chemical_classification, Mice, Inbred BALB C, Granuloma, biology, business.industry, Liver Diseases, General Medicine, Schistosoma mansoni, medicine.disease, biology.organism_classification, Schistosomiasis mansoni, Ferritin, Disease Models, Animal, 030104 developmental biology, chemistry, Transferrin, 030220 oncology & carcinogenesis, biology.protein, Cytokines, Therapeutics. Pharmacology, Hepatic fibrosis, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc257245ddc8204e777a41441c75a6fbTest
http://www.sciencedirect.com/science/article/pii/S0753332218365132Test

3

TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling

المؤلفون: Mark A. Burlingame, David Lee Nelson, R. Jeffrey Neitz, Alan R. Wolfe, Brian M. Suzuki, K. C. Lim, Leslie Z. Benet, Mark A. Scheideler, Conor R. Caffrey

المصدر: International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 3, Pp 571-586 (2018)
International journal for parasitology. Drugs and drug resistance, vol 8, iss 3
International Journal for Parasitology: Drugs and Drug Resistance

مصطلحات موضوعية: 0301 basic medicine, Male, Metabolite, Administration, Oral, Pharmacology, Praziquantel, chemistry.chemical_compound, Mice, 0302 clinical medicine, Drug Discovery, Anthelmintic, Schistosomiasis, Pharmacology (medical), Prodrugs, Arylsulfonates, biology, Chemistry, Schistosoma mansoni, Prodrug, 3. Good health, Infectious Diseases, Liver, 5.1 Pharmaceuticals, Medical Microbiology, Administration, Schistosoma haematobium, Schistosoma, Female, medicine.symptom, Development of treatments and therapeutic interventions, Alkylaminoalkanethiosulfuric acid, medicine.drug, Oral, 030231 tropical medicine, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, Schistosomicides, Rare Diseases, In vivo, parasitic diseases, medicine, Animals, Metabolomics, lcsh:RC109-216, Drug metabolism, Animal, Articles from the scientific meeting: "Anthelmintics: From Discovery to Resistance III", pp. 494 - 628, biology.organism_classification, Schistosomiasis mansoni, Vector-Borne Diseases, Disease Models, Animal, 030104 developmental biology, Orphan Drug, Good Health and Well Being, Mechanism of action, Disease Models, Parasitology, Drug disposition, Digestive Diseases