Best evidence topic: Does the presence of a large gallstone carry a higher risk of gallbladder cancer?
| العنوان: | Best evidence topic: Does the presence of a large gallstone carry a higher risk of gallbladder cancer? |
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| المؤلفون: | Talal Alshahri, Sabry Abounozha |
| المصدر: | Annals of Medicine and Surgery |
| بيانات النشر: | Elsevier, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, General surgery, Gallbladder adenocarcinoma, Large gallbladder stone, General Medicine, medicine.disease, Gallbladder cancer, 03 medical and health sciences, 0302 clinical medicine, Carry (investment), 030220 oncology & carcinogenesis, Large gallstone, Medicine, Gallstone 3 cm, 030211 gastroenterology & hepatology, Surgery, Best evidence, business, Original Research |
| الوصف: | A best evidence topic has been constructed using a described protocol. The three-part question addressed was: In a patient with symptomatic gallstone disease does the presence of a large sized gallstone associated with a higher risk of gallbladder cancer? Using the reported search, 3876 papers were found. 6 studies were deemed to be suitable to answer the question. The outcome assessed was the relationship between the presence of large sized gallstones and the risk of gallbladder cancer. It appears from the current available evidence that there is a strong association of a large sized gallstones and gallbladder cancer. Larger stones (>3 cm) have the greatest risk to develop gallbladder cancer, especially in symptomatic gallstone disease patients. Authors recommend special care for this patient's group and to warrant cholecystectomy when the clinical condition allows. Highlights • A strong relationship between the gallstone size and gallbladder cancer. • Stones larger than 3 cm have the highest risk. • Cholecystectomy is warranted when the clinical condition allows. |
| اللغة: | English |
| تدمد: | 2049-0801 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5a02dd83b41a8ffdbde8f7aee521f0Test http://europepmc.org/articles/PMC7777178Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ba5a02dd83b41a8ffdbde8f7aee521f0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20490801 |
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