Postural Orthostatic Tachycardia Syndrome (POTS) is a condition characterized by orthostatic tachycardia and associated intolerance. Common types are due to deconditioning. Less common types are neuropathic and hyperadrenergic POTS. Underlying hypovolemia and deconditioning are common in all types. The natural history is that of improving function, although symptoms tend to persist. Management consists of volume expansion (salt and fluids) and exercise. Drug treatment is helpful in the short term, although its value long term is unproven.
