Classification and nomenclature of metacaspases and paracaspases: no more confusion with caspases
| العنوان: | Classification and nomenclature of metacaspases and paracaspases: no more confusion with caspases |
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| المؤلفون: | Christiane Funk, Vanina E. Alvarez, Heinz D. Osiewacz, Juan José Cazzulo, Simon Stael, Boris Zhivotovsky, Chang Jae Choi, Frank Madeo, Jens Staal, Kailash C. Pandey, Lynn A. Megeney, Yigong Shi, Magali Casanova, Andrei Smertenko, Maurício F.M. Machado, Eric Lam, Renier A. L. van der Hoorn, Juergen Ruland, Ilana Berman-Frank, Panagiotis N. Moschou, Peter V. Bozhkov, Jeremy C. Mottram, Kay D. Bidle, Jerry Ståhlberg, Rudi Beyaert, Christopher M. Overall, Frédéric Bornancin, Kris Gevaert, Margot Thome, Assaf Vardi, Núria S. Coll, Patrick Gallois, Frank Van Breusegem, Thomas Nyström, Vishva M. Dixit, Marko Dolinar, Maria F. Suarez, Stephan Hailfinger, Nicolas Fasel, Emilio Gutierrez-Beltran, John A. Berges, Anna Linusson, Hannele Tuominen, Daniel Krappmann, Guy S. Salvesen, Marina Klemenčič, Elena A. Minina, Eugene V. Koonin |
| المساهمون: | Canaan, Stephane, Swedish University of Agricultural Sciences (SLU), Universiteit Gent = Ghent University (UGENT), Universidad Nacional de San Martin (UNSAM), University of Wisconsin - Milwaukee, University of Haifa [Haifa], Rutgers, The State University of New Jersey [New Brunswick] (RU), Rutgers University System (Rutgers), Novartis Institutes for BioMedical Research (NIBR), Laboratoire d'ingénierie des systèmes macromoléculaires (LISM), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of Texas at Austin [Austin], Centre for Research in Agricultural Genomics (CRAG), Genentech, Inc., Genentech, Inc. [San Francisco], University of Ljubljana, Université de Lausanne = University of Lausanne (UNIL), Umeå University, Universidade de Mogi das Cruces = University of Mogi das Cruzes (UMC), Karl-Franzens-Universität Graz, University of Ottawa [Ottawa], Institute of Molecular Biology and Biotechnology (IMBB-FORTH), Foundation for Research and Technology - Hellas (FORTH), University of York [York, UK], University of Gothenburg (GU), Goethe-University Frankfurt am Main, University of British Columbia (UBC), National Institute of Malaria Research [New Dehli, Inde] (NIMR), Indian Council of Medical Research [New Dehli] (ICMR), Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Sanford Burnham Prebys Medical Discovery Institute, Westlake University [Zhejiang], Washington State University (WSU), Universidad de Málaga [Málaga] = University of Málaga [Málaga], University of Oxford, Weizmann Institute of Science [Rehovot, Israël], Lomonosov Moscow State University (MSU), Knut and Alice Wallenberg Foundation, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Universiteit Gent = Ghent University [Belgium] (UGENT), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), University of Lausanne (UNIL), Karl-Franzens-Universität [Graz, Autriche], University of Oxford [Oxford], University of Graz, Technical University of Munich (TUM) |
| المصدر: | Molecular Cell Molecular Cell, 2020, 77 (5), pp.927-929. ⟨10.1016/j.molcel.2019.12.020⟩ CONICET Digital (CONICET) Consejo Nacional de Investigaciones Científicas y Técnicas instacron:CONICET Molecular Cell, Elsevier, 2020, 77 (5), pp.927-929. ⟨10.1016/j.molcel.2019.12.020⟩ Digital.CSIC. Repositorio Institucional del CSIC instname Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona Mol Cell MOLECULAR CELL Mol. Cell 77, 927-929 (2020) |
| بيانات النشر: | Elsevier, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Consensus, METACASPASES, Protein Conformation, [SDV]Life Sciences [q-bio], Computational biology, Article, purl.org/becyt/ford/1 [https], Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Terminology as Topic, medicine, Animals, Humans, CRYSTAL-STRUCTURE, purl.org/becyt/ford/1.6 [https], SPECIFICITY, Molecular Biology, Nomenclature, Caspase, PARACASPASES, ComputingMilieux_MISCELLANEOUS, Plant Proteins, 030304 developmental biology, Confusion, 0303 health sciences, biology, MALT1, Biology and Life Sciences, Cell Biology, 3. Good health, PROTEASES, [SDV] Life Sciences [q-bio], KEY, Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein, Caspases, biology.protein, CLAN CD, medicine.symptom, 030217 neurology & neurosurgery |
| الوصف: | Metacaspases and paracaspases are proteases that were first identified as containing a caspase-like structural fold (Uren et al., 2000). Like caspases, metacaspases and paracaspases are multifunctional proteins regulating diverse biological phenomena, such as aging, immunity, proteostasis, and programmed cell death. The broad phylogenetic distribution of metacaspases and paracaspases across all kingdoms of life and large variation of their biochemical and structural features complicate classification and annotation of the rapidly growing number of identified homologs. Establishment of an adequate classification and unified nomenclature of metacaspases and paracaspases is especially important to avoid frequent confusion of these proteases with caspases—a tenacious misnomer that unfortunately does not appear to decline with time. This Letter represents a consensus opinion of researchers studying different aspects of caspases, metacaspases, and paracaspases in various organisms, ranging from microbes to plants and animals. This work was supported by the Knut and Alice Wallenberg Foundation. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1097-2765 1097-4164 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca139f3f1cce5c86eb98c1db290f79e8Test https://doi.org/10.1016/j.molcel.2019.12.020Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ca139f3f1cce5c86eb98c1db290f79e8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10972765 10974164 |
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