دورية أكاديمية
Secondary metabolites of Hülle cells mediate protection of fungal reproductive and overwintering structures against fungivorous animals
| العنوان: | Secondary metabolites of Hülle cells mediate protection of fungal reproductive and overwintering structures against fungivorous animals |
|---|---|
| المؤلفون: | Li Liu, Christoph Sasse, Benedict Dirnberger, Oliver Valerius, Enikő Fekete-Szücs, Rebekka Harting, Daniela E Nordzieke, Stefanie Pöggeler, Petr Karlovsky, Jennifer Gerke, Gerhard H Braus |
| المصدر: | eLife, Vol 10 (2021) |
| بيانات النشر: | eLife Sciences Publications Ltd, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine LCC:Science LCC:Biology (General) |
| مصطلحات موضوعية: | Hülle cells, sexual development, secondary metabolites, xanthones, emodin, Medicine, Science, Biology (General), QH301-705.5 |
| الوصف: | Fungal Hülle cells with nuclear storage and developmental backup functions are reminiscent of multipotent stem cells. In the soil, Hülle cells nurse the overwintering fruiting bodies of Aspergillus nidulans. The genome of A. nidulans harbors genes for the biosynthesis of xanthones. We show that enzymes and metabolites of this biosynthetic pathway accumulate in Hülle cells under the control of the regulatory velvet complex, which coordinates development and secondary metabolism. Deletion strains blocked in the conversion of anthraquinones to xanthones accumulate emodins and are delayed in maturation and growth of fruiting bodies. Emodin represses fruiting body and resting structure formation in other fungi. Xanthones are not required for sexual development but exert antifeedant effects on fungivorous animals such as springtails and woodlice. Our findings reveal a novel role of Hülle cells in establishing secure niches for A. nidulans by accumulating metabolites with antifeedant activity that protect reproductive structures from animal predators. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2050-084X |
| العلاقة: | https://elifesciences.org/articles/68058Test; https://doaj.org/toc/2050-084XTest |
| DOI: | 10.7554/eLife.68058 |
| الوصول الحر: | https://doaj.org/article/52d3bada56f64ad284d6ec802974f495Test |
| رقم الانضمام: | edsdoj.52d3bada56f64ad284d6ec802974f495 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2050084X |
|---|---|
| DOI: | 10.7554/eLife.68058 |