دورية أكاديمية
A single clonal lineage of transmissible cancer identified in two marine mussel species in South America and Europe
| العنوان: | A single clonal lineage of transmissible cancer identified in two marine mussel species in South America and Europe |
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| المؤلفون: | Yonemitsu, Marisa A., Giersch, Rachael M., Polo-Prieto, Maria, Hammel, Maurine, Simon, Alexis, Cremonte, Florencia, Avilés, Fernando T., Merino-Véliz, Nicolás, Burioli, Erika AV, Muttray, Annette F., Sherry, James, Reinisch, Carol, Baldwin, Susan A., Goff, Stephen P., Houssin, Maryline, Arriagada, Gloria, Vázquez, Nuria Natalia, Bierne, Nicolas, Metzger, Michael J. |
| بيانات النشر: | eLife Sciences Publications |
| المجموعة: | CONICET Digital (Consejo Nacional de Investigaciones Científicas y Técnicas) |
| مصطلحات موضوعية: | DISEASES TRANSMISIBLES, CANCER, BIVALVES, ARGENTINE SEA, https://purl.org/becyt/ford/1.6Test, https://purl.org/becyt/ford/1Test |
| الوصف: | Transmissible cancers, in which cancer cells themselves act as an infectious agent, have been identified in Tasmanian devils, dogs, and four bivalves. We investigated a disseminated neoplasia affecting geographically distant populations of two species of mussels (Mytilus chilensis in South America and M. edulis in Europe). Sequencing alleles from four loci (two nuclear and two mitochondrial) provided evidence of transmissible cancer in both species. Phylogenetic analysis of cancer-associated alleles and analysis of diagnostic SNPs showed that cancers in both species likely arose in a third species of mussel (M. trossulus), but these cancer cells are independent from the previously identified transmissible cancer in M. trossulus from Canada. Unexpectedly, cancers from M. chilensis and M. edulis are nearly identical, showing that the same cancer lineage affects both. Thus, a single transmissible cancer lineage has crossed into two new host species and has been transferred across the Atlantic and Pacific Oceans and between the Northern and Southern hemispheres. ; Fil: Yonemitsu, Marisa A. Pacific Northwest Research Institute; Estados Unidos ; Fil: Giersch, Rachael M. Pacific Northwest Research Institute; Estados Unidos ; Fil: Polo-Prieto, Maria. Howard Hughes Medical Institute; Estados Unidos ; Fil: Hammel, Maurine. Université Montpellier II; Francia ; Fil: Simon, Alexis. Université Montpellier II; Francia ; Fil: Cremonte, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; Argentina ; Fil: Avilés, Fernando T. Universidad Andrés Bello; Chile ; Fil: Merino-Véliz, Nicolás. Universidad Andrés Bello; Chile ; Fil: Burioli, Erika AV. LABE´ O Frank Duncombe; Francia ; Fil: Muttray, Annette F. Environmental Resources Management; Canadá ; Fil: Sherry, James. Environment And Climate Change Canada; Canadá ; Fil: Reinisch, Carol. Environment And Climate Change Canada; Canadá ; Fil: Baldwin, Susan ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2050-084X |
| العلاقة: | info:eu-repo/semantics/altIdentifier/url/https://elifesciences.org/articles/47788Test; http://hdl.handle.net/11336/119454Test; Yonemitsu, Marisa A.; Giersch, Rachael M.; Polo-Prieto, Maria; Hammel, Maurine; Simon, Alexis; et al.; A single clonal lineage of transmissible cancer identified in two marine mussel species in South America and Europe; eLife Sciences Publications; Elife; 8; 11-2019; 1-21; CONICET Digital; CONICET |
| الإتاحة: | https://doi.org/10.7554/eLife.47788Test http://hdl.handle.net/11336/119454Test |
| حقوق: | info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by-nc-sa/2.5/arTest/ |
| رقم الانضمام: | edsbas.30EF722F |
| قاعدة البيانات: | BASE |
| تدمد: | 2050084X |
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