التفاصيل البيبلوغرافية
| العنوان: |
Advances in viral encephalitis: Viral transmission, host immunity, and experimental animal models. |
| المؤلفون: |
Dan Yang, Xiao-Jing Li, De-Zhen Tu, Xiu-Li Li, Bin Wei |
| المصدر: |
Zoological Research; 2023, Vol. 44 Issue 3, p525-542, 18p |
| مصطلحات موضوعية: |
VIRAL encephalitis, LABORATORY animals, ANIMAL models in research, ENCEPHALITIS, VIRAL transmission, IMMUNITY, VIRUS diseases, PLANT viruses |
| مستخلص: |
Viral infections have led to many public health crises and pandemics in the last few centuries. Neurotropic virus infection-induced viral encephalitis (VE), especially the symptomatic inflammation of the meninges and brain parenchyma, has attracted growing attention due to its high mortality and disability rates. Understanding the infectious routes of neurotropic viruses and the mechanism underlying the host immune response is critical to reduce viral spread and improve antiviral therapy outcomes. In this review, we summarize the common categories of neurotropic viruses, viral transmission routes in the body, host immune responses, and experimental animal models used for VE study to gain a deeper understanding of recent progress in the pathogenic and immunological mechanisms under neurotropic viral infection. This review should provide valuable resources and perspectives on how to cope with pandemic infections. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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