دورية أكاديمية
Retinopathy during interferon-β treatment for multiple sclerosis: case report and review of the literature
| العنوان: | Retinopathy during interferon-β treatment for multiple sclerosis: case report and review of the literature |
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| المؤلفون: | Calabresi P. |
| المساهمون: | Gaetani, L., Menduno, P. S., Cometa, F., Di Gregorio, M., Sarchielli, P., Cagini, C., Calabresi, P., Di Filippo, M. |
| بيانات النشر: | Dr. Dietrich Steinkopff Verlag GmbH and Co. KG |
| سنة النشر: | 2016 |
| المجموعة: | Università Cattolica del Sacro Cuore: PubliCatt |
| مصطلحات موضوعية: | Cotton wool spots, Interferon beta, Multiple sclerosis (MS), Retinal hemorrhages, Retinopathy, Adult, Female, Humans, Immunologic Factors, Interferon-beta, Multiple Sclerosis, Retinal Diseases, Settore MED/26 - NEUROLOGIA |
| الوصف: | The onset of new visual symptoms in patients with multiple sclerosis is often associated with a neuro-ophthalmologic manifestation of the disease. However, other possible differential diagnoses need to be ruled out, including drug-induced retinal side effects. Although uncommon, retinal side effects of interferon-beta formulations may occur, and need to be promptly recognized and treated by neurologists. In this manuscript, we report the case of a 37-year-old woman affected by multiple sclerosis diagnosed with interferon beta-associated retinopathy and we review the literature with regard to the epidemiology, clinical presentation, management and follow-up of interferon beta-associated retinopathy. Interferon-beta induced retinopathy seems to be an uncommon and a dose-related side effect in multiple sclerosis patients. Retinopathy tends to completely resolve after treatment discontinuation. Neurologists must be aware that immune-modulatory drugs, in particular interferon beta, have been reported to cause retinal side effects. In multiple sclerosis patients complaining of new visual symptoms during interferon-beta treatment, it is thus advisable to perform an ophthalmological assessment to rule out and properly manage retinopathy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/26292794; info:eu-repo/semantics/altIdentifier/wos/WOS:000372433600002; volume:263; issue:3; firstpage:422; lastpage:427; numberofpages:6; issueyear:2016; journal:JOURNAL OF NEUROLOGY; http://hdl.handle.net/10807/173355Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84960386049 |
| DOI: | 10.1007/s00415-015-7879-0 |
| الإتاحة: | https://doi.org/10.1007/s00415-015-7879-0Test http://hdl.handle.net/10807/173355Test |
| رقم الانضمام: | edsbas.12C0D4A9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00415-015-7879-0 |
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