دورية أكاديمية
Seroprevalence of HBV and HCV in primary hepatocellular carcinoma patients in Zimbabwe
| العنوان: | Seroprevalence of HBV and HCV in primary hepatocellular carcinoma patients in Zimbabwe |
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| المؤلفون: | Chin'ombe, Nyasha, Chavhunduka, Evans, Matarira, Hilda |
| المصدر: | Infectious Agents and Cancer ; http://www.infectagentscancer.comTest |
| بيانات النشر: | BioMed Central Ltd University of Cape Town Faculty of Health Sciences Division of Virology |
| سنة النشر: | 2009 |
| المجموعة: | University of Cape Town: OpenUCT |
| مصطلحات موضوعية: | Primary hepatocellular carcinoma, Hepatitis B virus |
| الوصف: | BACKGROUND:Primary hepatocellular carcinoma (PHC) is one of the most common cancers in Zimbabwe. Hepatitis B virus (HBV) and hepatitis C virus (HCV) are suspected to play a major role in causing this cancer. The objective of this study was to determine the seroprevalence of HBV and HCV in PHC at Parirenyatwa Referral Hospital in Zimbabwe. We evaluated the serological markers of the two viruses in patients with PHC using commercially available enzyme-linked immunosorbent kits. RESULTS: Out of the 60 patients with PHC, 48.3% were seropositive for HBV and 20.0% were seropositive for HCV. Co-infection by HCV and HBV was found in 8% of the patients. Only 13.3% of the health controls (blood donors) were positive for HBV. All the controls were negative for HCV. CONCLUSION: The high seropositivity of HBV and HCV in PHC in Zimbabwe suggested that the two viruses were a major cause of the cancer. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://hdl.handle.net/11427/14422Test; http://dx.doi.org/10.1186/1750-9378-4-15Test; https://open.uct.ac.za/bitstream/11427/14422/1/Chinombe_Seroprevalence_of_HBV_and_HCV_2009.pdfTest |
| DOI: | 10.1186/1750-9378-4-15 |
| الإتاحة: | https://doi.org/10.1186/1750-9378-4-15Test http://hdl.handle.net/11427/14422Test https://open.uct.ac.za/bitstream/11427/14422/1/Chinombe_Seroprevalence_of_HBV_and_HCV_2009.pdfTest |
| حقوق: | This is an Open Access article distributed under the terms of the Creative Commons Attribution License ; http://creativecommons.org/licenses/by/2.0Test ; 2009 Chin'ombe et al; licensee BioMed Central Ltd. |
| رقم الانضمام: | edsbas.A8B6CE64 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/1750-9378-4-15 |
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