دورية أكاديمية
Associations between atrial cardiopathy and cerebral amyloid: The ARIC-PET study
| العنوان: | Associations between atrial cardiopathy and cerebral amyloid: The ARIC-PET study |
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| المؤلفون: | Johansen, Michelle C, Mosley, Thomas H, Knopman, David S, Wong, Dean F, Ndumele, Chiadi, Shah, Amil M, Solomon, Scott D, Gottesman, Rebecca F |
| المصدر: | Open Access Publications |
| بيانات النشر: | Digital Commons@Becker |
| سنة النشر: | 2020 |
| المجموعة: | Washington University School of Medicine: Digital Commons@Becker |
| مصطلحات موضوعية: | Aged, 80 and over, Amyloid, Amyloid beta-Peptides, Aniline Compounds, Atherosclerosis, Atrial Fibrillation, Brain, Case-Control Studies, Cognitive Dysfunction, Cross-Sectional Studies, Echocardiography, Electrocardiography, Ethylene Glycols, Female, Heart Atria, Heart Diseases, Humans, Male, Natriuretic Peptide, Peptide Fragments, Positron-Emission Tomography, Risk Factors |
| الوصف: | Background Atrial fibrillation (AF) is a risk factor for cognitive decline, possibly from silent brain infarction. Left atrial changes in structure or function (atrial cardiopathy) can lead to AF but may impact cognition independently. It is unknown if AF or atrial cardiopathy also acts on Alzheimer disease-specific mechanisms, such as deposition of β-amyloid. Methods and Results A total of 316 dementia-free participants from the ARIC (Atherosclerosis Risk in Communities) study underwent florbetapir positron emission tomography, electrocardiography, and 2-dimensional echocardiography. Atrial cardiopathy was defined as ≥1: (1) left atrial volume index >34 mL/m |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | https://digitalcommons.wustl.edu/open_access_pubs/11201Test; https://digitalcommons.wustl.edu/context/open_access_pubs/article/12201/viewcontent/AssociationsBetweenAtrialCardiopathy.pdfTest; https://digitalcommons.wustl.edu/context/open_access_pubs/article/12201/filename/0/type/additional/viewcontent/jah35779_sup_0001_tabless1_s2.pdfTest |
| DOI: | 10.1161/JAHA.120.018399 |
| الإتاحة: | https://doi.org/10.1161/JAHA.120.018399Test https://digitalcommons.wustl.edu/open_access_pubs/11201Test https://digitalcommons.wustl.edu/context/open_access_pubs/article/12201/viewcontent/AssociationsBetweenAtrialCardiopathy.pdfTest https://digitalcommons.wustl.edu/context/open_access_pubs/article/12201/filename/0/type/additional/viewcontent/jah35779_sup_0001_tabless1_s2.pdfTest |
| رقم الانضمام: | edsbas.8772D7C6 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1161/JAHA.120.018399 |
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