Response of Home-Use Adaptive Pressure Modes to Simulated Transient Hypoventilation
| العنوان: | Response of Home-Use Adaptive Pressure Modes to Simulated Transient Hypoventilation |
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| المؤلفون: | Bruno Louis, Karl Leroux, Ghilas Boussaïd, Hélène Prigent, Frédéric Lofaso |
| المساهمون: | Equipe de Recherche Paramédicale sur le Handicap NeuroMoteur (ERPHAN), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay, Handicap neuromusculaire : Physiopathologie, Biothérapie et Pharmacologies appliquées (END-ICAP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Molecular virology and immunology – Physiopathology and therapeutic of chronic viral hepatitis (Team 18) (Inserm U955), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Biomécanique & Appareil Respiratoire (BAR), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | Respiratory Care Respiratory Care, Daedalus Enterprises Inc, 2020, 65 (9), pp.1258-1267. ⟨10.4187/respcare.07213⟩ |
| بيانات النشر: | Daedalus Enterprises, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, medicine.medical_specialty, Central sleep apnea, Respiratory rate, [SDV]Life Sciences [q-bio], Hyperpnea, Critical Care and Intensive Care Medicine, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, bench study, Tidal Volume, medicine, Humans, Cheyne-Stokes Respiration, Tidal volume, servomechanism, Continuous Positive Airway Pressure, lung model, adaptive servo ventilation, business.industry, pressure support, non-invasive ventilation, Hypoventilation, General Medicine, medicine.disease, Sleep Apnea, Central, 030228 respiratory system, Breathing, Cardiology, Transient (oscillation), medicine.symptom, business, Hypopnea |
| الوصف: | BACKGROUND: Adaptive servoventilation (ASV) is a recently developed ventilation mode designed to stabilize ventilation in patients with central sleep apnea and Cheyne-Stokes respiration. Alternatively, modes aiming to maintain average ventilation over several breaths, such as average volume-assured pressure support (AVAPS) and intelligent volume-assured pressure support (iVAPS), could be efficient during ventilation instability by reducing central events. These modes are available on a variety of devices. This bench evaluation studied the response of these different modes and devices to simulated transient hypoventilation events. METHODS: Three home ventilation devices operating in ASV modes (AirCurve 10 CS Pacewave, ResMed; DreamStation autoSV, Philips; Prisma CR, Lowenstein) and 2 ventilators with the AVAPS mode (DreamStation BiPAP, Philips; Lumis 150 iVAPS, ResMed) were evaluated during transient central hypopnea/hypoventilation simulations characterized by a constant breathing frequency of 15 breaths/min and a progressive decrease of tidal volume (VT) from 500 mL to 50 mL, in 18, 12, 9, and 6 breaths, respectively, followed by a progressive return to the baseline at the same rate. RESULTS: The AirCurve 10 CS Pacewave reacted to a VT decrease between 80% and 50% of baseline VT. DreamStation BiPAP and Prisma CR reacted when VT decreased to between 60% and 30% of baseline VT, whereas the AVAPS response to hypopnea occurred during the crescendo phase of hypopnea/hypoventilation VT. The iVAPS response was between that of the AirCurve 10 CS Pacewave and the other ASV devices. Among the ASV devices, the minimum VT was higher with AirCurve 10 CS Pacewave, followed by the Prisma CR and the DreamStation BiPAP. Minimum VT was not influenced by AVAPS and was improved by iVAPS without outperforming the AirCurve 10 CS Pacewave. Maximum VT was increased by iVAPS, whereas ASV devices did not induce a significant VT overshoot. CONCLUSIONS: ASV devices improved central hypopnea/hypoventilation events without inducing hyperpnea events and therefore were better adapted than AVAPS and iVAPS devices, with notable differences in their responses to hypoventilation events. |
| تدمد: | 1943-3654 0020-1324 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1259b8e893b7c1304ed65eb49b4220Test https://doi.org/10.4187/respcare.07213Test |
| رقم الانضمام: | edsair.doi.dedup.....1d1259b8e893b7c1304ed65eb49b4220 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19433654 00201324 |
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