دورية أكاديمية

Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myeloma ; Uyku kalitesi ve geriatrik 8 (G8) skorunun multiple myelomlu yaşlı hastalarda kemoterapi ile değişimleri

التفاصيل البيبلوغرافية
العنوان: Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myeloma ; Uyku kalitesi ve geriatrik 8 (G8) skorunun multiple myelomlu yaşlı hastalarda kemoterapi ile değişimleri
المؤلفون: KOYUNCU, Mahmut Bakır, ÇAVUŞOĞLU, Çağatay, TOMBAK, Anıl, UÇAR, Mehmet Ali, AKDENİZ, Aydan, TİFTİK, Eyüp Naci
المصدر: Volume: 46, Issue: 4 1574-1580 ; 2602-3032 ; 2602-3040 ; Cukurova Medical Journal
بيانات النشر: Çukurova Üniversitesi
Cukurova University
سنة النشر: 2021
المجموعة: DergiPark Akademik (E-Journals)
مصطلحات موضوعية: Multiple myeloma,sleep quality,geriatric scores, multiple myelom,uyku kalitesi,geriatrik değerlendirme
الوصف: Purpose: The aim of this study was to evaluate the sleep quality of older patients with multiple myeloma before and after chemotherapy and investigate factors affecting sleep quality. Materials and Methods: A total of 108 patients with newly diagnosed multiple myeloma were included in the study. Geriatric 8 (G8) and Pittsburgh Sleep Quality Index scores were calculated for the patients at the time of diagnosis, and the changes in these scores were evaluated after three cycles of chemotherapy. Results: At the time of diagnosis, 63 (58.3%) of the patients had sleep disturbances. The sleep disturbance rate decreased to 41.7% after chemotherapy. There was no statistically significant difference in the total G8 score before and after treatment. In logistic regression analyses, the serum calcium level, pre-treatment G8 score, and response to chemotherapy were predictors of sleep quality. Increases in sleep quality were significantly higher in patients with good responses to chemotherapy. Conclusion: Sleep disturbances are a common problem in older patients with multiple myeloma. Our study demonstrated that sleep quality increased with chemotherapy, and patients with low sleep quality had worse responses to treatment. Therefore, there is a need for measures and treatments to increase the sleep quality of these patients. ; Amaç: Bu çalışmada multipl miyelomlu yaşlı hastaların kemoterapi öncesi ve sonrası uyku kalitesini değerlendirmeyi ve uyku kalitesini etkileyen faktörleri araştırmayı amaçladık.Gereç ve Yöntem: Yeni tanı konmuş Multipl miyelomlu toplam 108 hasta çalışmaya dahil edildi. Hastaların tanı anında Geriatrik 8 (G8) ve Pittsburgh Uyku Kalitesi İndeksi skorları hesaplandı ve bu skorlardaki değişiklikler üç kür kemoterapi sonrası değerlendirildi. Bulgular: Hastaların 63'ünde (,3) tanı anında uyku bozukluğu vardı. Kemoterapiden sonra uyku bozukluğu oranının .7'ye düştüğü görüldü. Tedavi öncesi ve sonrası toplam G8 skorunda istatistiksel olarak anlamlı bir fark yoktu. Lojistik regresyon ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
العلاقة: https://dergipark.org.tr/tr/download/article-file/1903140Test; https://dergipark.org.tr/tr/pub/cumj/issue/62103/977316Test
الإتاحة: https://dergipark.org.tr/tr/pub/cumj/issue/62103/977316Test
رقم الانضمام: edsbas.BFCF3330
قاعدة البيانات: BASE