Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor
| العنوان: | Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor |
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| المؤلفون: | Inge Behroozfard, Jennifer Peralez, Holly C. Beale, Katrina Learned, Arun Rangaswami, Sheri L. Spunt, Florette K. Hazard, Robert Currie, David Haussler, Norman J. Lacayo, Jacob Pfeil, E. Alejandro Sweet-Cordero, A. Geoffrey Lyle, Marcus R. Breese, Avanthi Tayi Shah, Alex G. Lee, Sofie R. Salama, Stanley G. Leung, Ellen Kephart, Isabel Bjork, Du Linh Lam, Ann Durbin, Olena M. Vaske, Lauren Sanders |
| المصدر: | Cold Spring Harbor Molecular Case Studies Cold Spring Harbor molecular case studies, vol 5, iss 5 |
| بيانات النشر: | Cold Spring Harbor Laboratory Press, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Research Report, Pathology, medicine.medical_specialty, endocrine system, endocrine system diseases, RNA-Seq, Immature Ovarian Teratoma, Whole Exome Sequencing, Rare Diseases, Gene expression, Exome Sequencing, Genetics, Medicine, Humans, Ovarian Teratoma, Child, Peritoneal Neoplasms, Cancer, Pediatric, Ovarian Neoplasms, Base Sequence, business.industry, Sequence Analysis, RNA, Prevention, Human Genome, Teratoma, RNA, Pediatric Tumor, General Medicine, Glioma, medicine.disease, Prognosis, female genital diseases and pregnancy complications, Ovarian Cancer, neoplasm of the nervous system, Immature teratoma, Female, Germ cell tumors, business, Sequence Analysis |
| الوصف: | Gliomatosis peritonei is a rare pathologic finding that is associated with ovarian teratomas and malignant mixed germ cell tumors. The occurrence of gliomatosis as a mature glial implant can impart an improved prognosis to patients with immature ovarian teratoma, making prompt and accurate diagnosis important. We describe a case of recurrent immature teratoma in a 10-yr-old female patient, in which comparative analysis of the RNA sequencing gene expression data from the patient's tumor was used effectively to aid in the diagnosis of gliomatosis peritonei. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2373-2873 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44d99b61632ab97fa0a86974ae58579Test http://europepmc.org/articles/PMC6824255Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f44d99b61632ab97fa0a86974ae58579 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23732873 |
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