المؤلفون: Philipp Mathé, Katja Schmidt, Viktoria Schindler, Ahmad Fawzy, Tilman Schultze, Reinhard E. Voll, David Pauli, Milena Popova, Franziska Schauer, Tobias Eisenberg

المصدر: Emerging Infectious Diseases, Vol 30, Iss 3, Pp 608-610 (2024)

مصطلحات موضوعية: Rat-Bite Fever, Streptobacillus moniliformis, endocarditis, serology, zoonoses, Janeway lesions, Medicine, Infectious and parasitic diseases, RC109-216

الوصف: We describe a case of endocarditis caused by Streptobacillus moniliformis bacteria, a known cause of rat-bite fever, in a 32-year-old woman with pet rats in Germany. The patient had a strong serologic response, with high IgM and IgG titers. Serologic analysis is a promising tool to identify S. moniliformis bacterial infection.

وصف الملف: electronic resource

العلاقة: https://wwwnc.cdc.gov/eid/article/30/3/23-0917_articleTest; https://doaj.org/toc/1080-6040Test; https://doaj.org/toc/1080-6059Test

الوصول الحر: https://doaj.org/article/2f851e35fce04f92b47074445c8cae27Test

المؤلفون: Yoshihiko Ogawa, Kei Kasahara, Sang-Tae Lee, Takamitsu Ito, Hideo Hasegawa, Sachie Hirose, Shigeru Santo, Atsushi Yoshida, Ryuichi Nakano, Hisakazu Yano, Keiichi Mikasa

المصدر: Emerging Infectious Diseases, Vol 24, Iss 7, Pp 1377-1379 (2018)

مصطلحات موضوعية: rat-bite fever, Streptobacillus notomytis, Streptobacillus moniliformis, 16S ribosomal RNA gene, bacteria, zoonoses, Medicine, Infectious and parasitic diseases, RC109-216

الوصف: We report a case of rat-bite fever in a 94-year-old woman with Streptobacillus notomytis infection. We established an epidemiologic link between exposure to rats and human infection by performing nested PCRs that detected S. notomytis in the intraoral swab specimens obtained from rats captured in the patient’s house.

وصف الملف: electronic resource

العلاقة: https://wwwnc.cdc.gov/eid/article/24/7/17-1580_articleTest; https://doaj.org/toc/1080-6040Test; https://doaj.org/toc/1080-6059Test

الوصول الحر: https://doaj.org/article/868290adc9574c56a52e720290ecdb10Test

المؤلفون: Tobias Eisenberg, Simon Poignant, Youenn Jouan, Ahmad Fawzy, Werner Nicklas, Christa Ewers, Laurent Mereghetti, Antoine Guillon

المصدر: Emerging Infectious Diseases, Vol 23, Iss 4, Pp 719-721 (2017)

مصطلحات موضوعية: acute tetraplegia, rat bite fever, snake keeper, transmission, Streptobacillus moniliformis, bacteria, Medicine, Infectious and parasitic diseases, RC109-216

الوصف: We report acute tetraplegia caused by rat bite fever in a 59-year old man (snake keeper) and transmission of Streptobacillus moniliformis. We found an identical characteristic bacterial pattern in rat and human samples, which validated genotyping-based evidence for infection with the same strain, and identified diagnostic difficulties concerning infection with this microorganism.

وصف الملف: electronic resource

العلاقة: https://wwwnc.cdc.gov/eid/article/23/4/16-1987_articleTest; https://doaj.org/toc/1080-6040Test; https://doaj.org/toc/1080-6059Test

الوصول الحر: https://doaj.org/article/bb4c38334643495eb4dd2836f64d8e6eTest

المؤلفون: Eisenberg, Tobias, Poignant, Simon, Jouan, Youenn, Fawzy, Ahmad, Nicklas, Werner, Ewers, Christa, Mereghetti, Laurent, Guillon, Antoine

المساهمون: Hessian State Laboratory, Partenaires INRAE, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Justus-Liebig-Universität Gießen = Justus Liebig University (JLU), Cairo University, German Cancer Research Center - Deutsches Krebsforschungszentrum Heidelberg (DKFZ), Infectiologie et Santé Publique (UMR ISP), Institut National de la Recherche Agronomique (INRA)-Université de Tours (UT)

المصدر: ISSN: 1080-6040.

مصطلحات موضوعية: France, PCR, bacteria, multilocus variant analysis, rat bite fever, snake keeper, snakes, species specificity, variable number tandem repeat analysis, zoonoses, Streptobacillus moniliformis, acute tetraplegia, rats, reptiles, transmission, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

الوصف: International audience ; We report acute tetraplegia caused by rat bite fever in a 59-year old man (snake keeper) and transmission of Streptobacillus moniliformis. We found an identical characteristic bacterial pattern in rat and human samples, which validated genotyping-based evidence for infection with the same strain, and identified diagnostic difficulties concerning infection with this microorganism.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28322713; hal-02625170; https://hal.inrae.fr/hal-02625170Test; https://hal.inrae.fr/hal-02625170/documentTest; https://hal.inrae.fr/hal-02625170/file/2017_Eisenberg_Emerg%20Infect%20Dis_1.pdfTest; PRODINRA: 417763; PUBMED: 28322713; WOS: 000396824400037

الإتاحة: https://doi.org/10.3201/eid2304.161987Test
https://hal.inrae.fr/hal-02625170Test
https://hal.inrae.fr/hal-02625170/documentTest
https://hal.inrae.fr/hal-02625170/file/2017_Eisenberg_Emerg%20Infect%20Dis_1.pdfTest

المؤلفون: Ali Uddin, Tung Phan, Mohamed Yassin

المصدر: Emerging Infectious Diseases, Vol 27, Iss 12, Pp 3198-3199 (2021)
Emerging Infectious Diseases

مصطلحات موضوعية: Microbiology (medical), Fastidious organism, musculoskeletal diseases, MALDI-TOF, Epidemiology, Inflammatory arthritis, Rat-bite fever, Infectious and parasitic diseases, RC109-216, Streptobacillus, polyarthritis, Streptobacillus moniliformis, Microbiology, Rare case, medicine, Research Letter, Animals, Humans, septic arthritis, bacteria, Arthritis, Infectious, biology, business.industry, bacterial zoonoses, Septic Polyarthritis Caused by Streptobacillus moniliformis, medicine.disease, biology.organism_classification, zoonotic infections, United States, zoonoses, rat-bite fever, Moniliformis, rats, Infectious Diseases, bacterial infections, Medicine, Polyarthritis, Septic arthritis, business

الوصف: Streptobacillus moniliformis is a pleomorphic, fastidious gram-negative bacillus that colonizes rodent respiratory tracts and causes rat-bite fever in humans. Rat-bite fever is associated with septic arthritis, usually monoarticular or pauciarticular. We report a rare case of polyarticular septic arthritis caused by S. moniliformis; the disease was initially misdiagnosed as inflammatory arthritis.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04548bf61c9e6b1d6595149a264e501cTest
https://wwwnc.cdc.gov/eid/article/27/12/21-0649_articleTest

المؤلفون: Byron Breedlove

المصدر: Emerging Infectious Diseases, Vol 28, Iss 2, Pp 495-496 (2022)
Emerging Infectious Diseases

مصطلحات موضوعية: hantavirus infection, chikungunya, London School of Hygiene & Tropical Medicine, P.R. Morley Horder, Epidemiology, sleeping sickness, vector-borne infections, art science connection, Deadly, Infectious and parasitic diseases, RC109-216, bedbug, Zika virus, protozoa, fleas, Lyme disease, bacteria, African trypanosomiasis, body louse, Plasmodium spp, Tsetse fly, public health, Heartland virus disease, transmission, babesiosis, Dangerous, Gilded Vectors of Disease, rat-bite fever, Anopheles spp, Infectious Diseases, rodents, Crimean-Congo hemorrhagic fever, Medicine, Rocky Mountain spotted fever, Lassa fever, Microbiology (medical), sandflies, salmonellosis, malaria, parasites, ticks, yellow fever, emerging infectious diseases, about the cover, Aedes spp, small mammals, viruses, anaplasmosis, art and medicine, leishmaniasis, mosquitoes, West Nile fever, dengue virus, louse-borne relapsing fever, Deadly, Dangerous, and Decorative Creatures, plague, zoonoses, ehrlichiosis, and Decorative Creatures, murine typhus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2ea8a5932743fdbd588824e3654dddTest
https://wwwnc.cdc.gov/eid/article/28/2/ac-2802_articleTest

المؤلفون: Michael E. Schachter, Lindsay Wilcox, Neil Rau, Deborah Yamamura, Shirley Brown, Christine H. Lee

المصدر: Emerging Infectious Diseases, Vol 12, Iss 8, Pp 1301-1302 (2006)

مصطلحات موضوعية: Rat-bite fever, Streptobacillus moniliformis, Spirillum minus, letter, Canada, Medicine, Infectious and parasitic diseases, RC109-216

العلاقة: https://wwwnc.cdc.gov/eid/article/12/8/06-0044_articleTest; https://doaj.org/toc/1080-6040Test; https://doaj.org/toc/1080-6059Test; https://doaj.org/article/5944992a477d4534a980085565c0a639Test

الإتاحة: https://doi.org/10.3201/eid1208.060044Test
https://doaj.org/article/5944992a477d4534a980085565c0a639Test

المؤلفون: Deborah Yamamura, Shirley Brown, Lindsay Wilcox, Michael E. Schachter, Christine H. Lee, Neil Rau

المصدر: Emerging Infectious Diseases, Vol 12, Iss 8, Pp 1301-1302 (2006)
Emerging Infectious Diseases

مصطلحات موضوعية: Microbiology (medical), medicine.medical_specialty, Pathology, Canada, Epidemiology, Rat-bite fever, letter, lcsh:Medicine, Streptobacillus moniliformis, lcsh:Infectious and parasitic diseases, medicine, Maculopapular rash, Spirillum minus, lcsh:RC109-216, Letters to the Editor, biology, business.industry, lcsh:R, medicine.disease, biology.organism_classification, Dermatology, Rash, Moniliformis, Infectious Diseases, Chills, medicine.symptom, business, Meningitis

الوصف: To the Editor: Rat-bite fever was once considered an infection exclusive to children living in poverty; however, dense urban housing and changing pet-keeping practices may be altering this profile (1,2). To date, ≈200 cases of rat-bite fever have been reported in the United States (3), and a recent study reported a 2-fold increased incidence in California during the 1990s (1). We report on 2 cases that occurred in Ontario, Canada, in the early 2000s. The first case occurred in a previously healthy 29-year-old man who was bitten on the finger by a pet rat. The wound healed spontaneously. After 24 hours, fever and emesis developed; 4 days later, diffuse maculopapular rash and migratory arthritis of the knees, ankles, and finger joints ensued. Physical examination showed a maculopapular rash over the lower extremities, an effusion of the left knee, and a warm, erythematous left ankle. Laboratory investigations showed hemoglobin level of 134 g/L, leukocyte count of 16.0×109/L, and neutrophil count of 13.8×109/L. Aspiration of the knee produced 70 cm3 of cloudy fluid; synovial fluid analysis showed 666×106/L leukocytes with a predominance of neutrophils. Ceftriaxone, 2 g once a day, was given intravenously for 7 days. Although symptoms improved within 24 hours, the effusion recurred within 48 hours of discontinuing the initial course of ceftriaxone. The knee was surgically drained, and ceftriaxone was continued for 5 weeks. Systemic symptoms and the effusion resolved. The second case occurred in a previously healthy 9-year-old girl who had mucosal contact with a pet rat. She sought treatment after 7 days of generalized maculopapular and pustular rash and 10 days of fever and headache. She had an associated asymmetric, migratory arthritis. Physical examination showed superficial scratches from the rat; temperature of 39.6°C; heart rate of 102 bpm; swelling, erythema, and decreased range of motion in several joints; and pustular lesions on the soles of the feet. The patient’s leukocyte count was 8.3×109/L. Synovial fluid from the knee showed 45.5×106/L leukocytes with 89% neutrophils; the culture showed no growth. Gram stains of blood and pustule swabs showed large, pleomorphic, gram-negative bacilli with long filaments and irregular swellings. Growth occurred on the blood culture after 28 hours of aerobic incubation at 35°C in 10% horse serum. Characteristic puff-ball colonies of Streptobacillus moniliformis were seen in supplemented thioglycolate broth. Identification of the organism was confirmed by using the Sherlock (MIDI Inc., Newark, DE, USA) system. The major cellular fatty acid components of the isolate matched an S. moniliformis reference strain. The patient received penicillin and gentamicin intravenously for 6 days and was discharged home with a 10-day regimen of amoxicillin. One year later, she remained asymptomatic. Rat-bite fever commonly results from infection with the zoonotic pathogens S. moniliformis and Spirillum minus. S. moniliformis is more common in Western countries, and S. minus predominates in Asia (3). S. moniliformis colonizes the nasopharynx of healthy rats (4) and is transmitted by the bite or scratch of rats, squirrels, mice, guinea pigs, and, rarely, cats and other rodent predators. Occasionally, it is transmitted by ingestion of contaminated milk or water (5,6). The site of inoculation with S. moniliformis usually heals before systemic symptoms develop. After the incubation period of 1 to 22 days, patients experience fever, chills, myalgia, headache, and rash. The rash consists of macules, vesicles, and pustules on the extremities; soles and palms are frequently involved. Joint symptoms range from polyarthralgia to migratory polyarthritis with purulent effusions. A nonsuppurative migratory polyarthritis occurs in ≈50% of patients (5,7). In rare cases, rash and arthritis may be absent (8). When S. minus (a spirochete) is introduced by rat bite, the bite wound initially heals but then ulcerates, followed by regional lymphadenopathy and a distinctive rash of red and purple plaques. Arthritic symptoms are rare (9). Complications of rat-bite fever include destructive joint disease, pericarditis, endocarditis, abscesses, pneumonia, parotitis, pancreatitis, and, rarely, meningitis and amnionitis. Development of endocarditis results in a mortality rate of up to 50% (5). S. moniliformis can be isolated and cultured from synovial fluid, blood, and abscesses. By contrast, S. minus has not been recovered on artificial media but can be seen by using dark-field microscopy with Giemsa or Wright stains. Laboratory personnel must be notified when rat-bite fever is suspected because S. moniliformis does not grow in a routine sheep blood or MacConkey agar; it requires rat or horse serum, defibrinated blood, or ascitic fluid to sustain growth. Growth of S. moniliformis is inhibited by sodium polyanetholesulfonate, a substance that is added to blood culture bottles to inhibit the antimicrobial action of blood (4,8). Optimal treatment for rat-bite fever is penicillin G given intravenously for 7 to 10 days, followed by penicillin V taken orally for 7 days. Alternatively, tetracycline may be used (5,7,9). Although rat-bite fever is uncommon, it is increasingly seen as a result of changing patterns of urban living and pet-keeping practices. If unrecognized, this infection can have debilitating sequelae and can be life-threatening.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5e72299c3783a84d960a7019ce2301Test
https://wwwnc.cdc.gov/eid/article/12/8/06-0044_articleTest

المؤلفون: Shanmugasundaram S, Thangam Menon, Nandhakumar Balakrishnan, Ramasamy Alagesan

المصدر: Emerging Infectious Diseases, Vol 12, Iss 6, Pp 1037-1038 (2006)
Emerging Infectious Diseases

مصطلحات موضوعية: Microbiology (medical), Pathology, medicine.medical_specialty, Streptobacillus, Epidemiology, Haverhill fever, Rat-bite fever, letter, India, lcsh:Medicine, Gastroenterology, Streptobacillus moniliformis, lcsh:Infectious and parasitic diseases, Internal medicine, medicine, Endocarditis, lcsh:RC109-216, Letters to the Editor, biology, business.industry, lcsh:R, biology.organism_classification, medicine.disease, congenital heart disease, Moniliformis, Infectious Diseases, Spirillum minus, Gentamicin, business, medicine.drug

الوصف: To the Editor: Streptobacillus moniliformis is a facultatively anaerobic, pleomorphic, gram-variable bacillus often seen in chains and as long unbranched filaments. It is found in the nasopharynx and oropharynx of wild and laboratory rats. Human infections result either from rodent bites (rat bite fever) or contaminated milk or other foods (Haverhill fever). The most common manifestations of infection are arthralgia, fever, and rash; endocarditis occurs as a rare complication (1). We report a case of S. moniliformis endocarditis in India in a patient with congenital heart disease. An 18-year-old man was admitted to the Department of Cardiology at the Government General Hospital in Chennai, India, in November 2005, with a fever of 2 months' duration with cough, epistaxis, palpitations, and persistent joint pain. His medical history indicated congenital heart disease with a ventricular septal defect. On physical examination, his blood pressure was 100/70 mm Hg, pulse rate was 100 beats/min, and temperature was 38.5°C. Laboratory tests showed a leukocyte count of 7,600/μL, a platelet count of 127,000/μL, and an erythrocyte sedimentation rate of 70 mm/h. An electrocardiogram showed normal sinus rhythm. A transthoracic echocardiogram demonstrated a ventricular septal defect and vegetations on the septal leaflet of the tricuspid valve. Three blood cultures were prepared, and treatment with antimicrobial drugs (intravenous penicillin G, 3 × 106 U every 6 h, and gentamicin, 50 mg every 8 h for 4 weeks) was initiated. The blood cultures were incubated at 37°C in an atmosphere of 5%–10% CO2. Characteristic white, downy, crumblike granules were observed on the surface of the erythrocytes in all 3 cultures within 18–24 h of incubation. Characteristic puff balls were seen after 48 h of incubation. Gram-stained smears showed gram-negative bacilli in long chains. Cultures were subcultured onto 5% sheep blood agar plates and MacConkey agar plates. The plates were incubated at 37°C in an atmosphere of 5%–10% CO2. After 18–24 h of incubation, growth was seen on the sheep blood agar plates. Colonies were 1–2 mm in diameter, gray, smooth, and butyrous. A Gram stain of these colonies identified gram-variable, pleomorphic coccobacilli that were negative for catalase, oxidase, urease, and citrate, and did not produce indole or reduce nitrate. Antimicrobial susceptibility testing was performed by using the Kirby-Bauer disk diffusion method according to recommendations of the National Committee for Clinical Laboratory Standards (2). The isolate was sensitive to penicillin G, ceftriaxone, cephalexin, amoxicillin, gentamicin, and erythromycin. The patient responded well to treatment and became afebrile within 48 h after initiation of therapy. Treatment with antimicrobial drugs was continued for 4 weeks. The blood cultures were negative when repeated after 2 weeks. The patient had an uneventful recovery and was discharged from the hospital. Rat bite fever is a zoonosis caused by either Streptobacillus moniliformis or Spirillum minus (1,3). S. moniliformis is found in the nasopharynx of small rodents, especially rats. Rats that are carriers have no symptoms but can effectively transmit the infection by bite or through infected body fluids such as urine. This patient had a history of living in a rat-infested area, and admitted having been bitten by a rat several months before the onset of symptoms. However, we considered it unlikely that disease contracted by a rat bite would take months to be manifested. Thus, it is more likely that he contracted the infection from food or water contaminated with rat excreta. Endocarditis is a rare complication of S. moniliformis infection, and cardiac valvular abnormalities have been reported in ≈50% of cases (4). This patient, however, had only a small ventricular septal defect. This is the first report of S. moniliformis endocarditis from India.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc64048c624e2d5ce38edf43ded6591aTest
https://wwwnc.cdc.gov/eid/article/12/6/06-0069_articleTest