دورية أكاديمية

SH3 domains direct cellular localization of signaling molecules.

التفاصيل البيبلوغرافية
العنوان: SH3 domains direct cellular localization of signaling molecules.
المؤلفون: Bar-Sagi, D., Rotin, D., Batzer, A., Mandiyan, V., Schlessinger, J.
المصدر: Cell. 7/16/93, Vol. 74 Issue 1, p83. 9p. 19 Black and White Photographs, 2 Diagrams, 2 Charts.
مصطلحات موضوعية: *CYTOLOGICAL research, *PHYSIOLOGICAL research
مستخلص: Describes the cellular distribution of the SH2 and SH3 domains of phospholipase C-gamma (PLC-gamma) and of the adaptor protein GRB2 following microinjection into living rat embryo fibroblasts. Immunofluorescence microscopy; Localization to actin cytoskeleton; Diffuse cytoplasmic distribution; Tagetting of signaling molecules to specific subcellular locations.
قاعدة البيانات: Academic Search Index
الوصف
تدمد:00928674
DOI:10.1016/0092-8674(93)90296-3