التفاصيل البيبلوغرافية
| العنوان: |
Autoimmune Hepatitis Triggered by Anti-TNF- Therapy |
| المؤلفون: |
Satoshi Nakayama |
| بيانات النشر: |
Case Reports in Medicine |
| سنة النشر: |
2013 |
| المجموعة: |
Hindawi Publishing Corporation |
| الوصف: |
Autoimmune hepatitis (AIH) is occasionally triggered by drug treatments. Recently, as biological agents are becoming widely used for autoimmune disorders, there have been a growing number of reports of the development of autoimmune processes related to these agents. A 52-year-old Japanese woman with psoriasis developed liver damage two months after initiation of anti-TNF-α therapy with adalimumab. Liver histological findings were compatible with AIH, and positive conversions of ANAs were detected. The patient was treated with prednisolone and had a good response. While some cases of AIH triggered by anti-TNF-α therapies have been reported, the pathogenesis remains unspecified. When elevation of liver enzymes is observed with high IgG levels and seropositivity of ANA during the course of anti-TNF-α therapy, liver biopsy findings may be essential and important to make definitive diagnosis of AIH. |
| نوع الوثيقة: |
report |
| اللغة: |
English |
| العلاقة: |
https://doi.org/10.1155/2013/561748Test |
| DOI: |
10.1155/2013/561748 |
| الإتاحة: |
https://doi.org/10.1155/2013/561748Test |
| حقوق: |
Copyright © 2013 Satoshi Nakayama. |
| رقم الانضمام: |
edsbas.C5A50387 |
| قاعدة البيانات: |
BASE |
