Air dispersal of respiratory viruses other than severe acute respiratory coronavirus virus 2 (SARS-CoV-2) and the implication on hospital infection control
| العنوان: | Air dispersal of respiratory viruses other than severe acute respiratory coronavirus virus 2 (SARS-CoV-2) and the implication on hospital infection control |
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| المؤلفون: | Shuk-Ching Wong, Veronica Wing-Man Chan, Christine Ho-Yan AuYeung, Jonathan Hon-Kwan Chen, Cyril Chik-Yan Yip, Simon Yung-Chun So, Xin Li, David Christopher Lung, Anita Man-Ching Tsang, Kelvin Kai-Wang To, Kwok-Yung Yuen, Vincent Chi-Chung Cheng |
| المصدر: | Infection Control & Hospital Epidemiology. 44:768-773 |
| بيانات النشر: | Cambridge University Press (CUP), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Microbiology (medical), Infectious Diseases, Epidemiology |
| الوصف: | Background:Air dispersal of respiratory viruses other than SARS-CoV-2 has not been systematically reported. The incidence and factors associated with air dispersal of respiratory viruses are largely unknown.Methods:We performed air sampling by collecting 72,000 L of air over 6 hours for pediatric and adolescent patients infected with parainfluenza virus 3 (PIF3), respiratory syncytial virus (RSV), rhinovirus, and adenovirus. The patients were singly or 2-patient cohort isolated in airborne infection isolation rooms (AIIRs) from December 3, 2021, to January 26, 2022. The viral load in nasopharyngeal aspirates (NPA) and air samples were measured. Factors associated with air dispersal were investigated and analyzed.Results:Of 20 singly isolated patients with median age of 30 months (range, 3 months–15 years), 7 (35%) had air dispersal of the viruses compatible with their NPA results. These included 4 (40%) of 10 PIF3-infected patients, 2 (66%) of 3 RSV-infected patients, and 1 (50%) of 2 adenovirus-infected patients. The mean viral load in their room air sample was 1.58×103 copies/mL. Compared with 13 patients (65%) without air dispersal, these 7 patients had a significantly higher mean viral load in their NPA specimens (6.15×107 copies/mL vs 1.61×105 copies/mL; P < .001). Another 14 patients were placed in cohorts as 7 pairs infected with the same virus (PIF3, 2 pairs; RSV, 3 pairs; rhinovirus, 1 pair; and adenovirus, 1 pair) in double-bed AIIRs, all of which had air dispersal. The mean room air viral load in 2-patient cohorts was significantly higher than in rooms of singly isolated patients (1.02×104 copies/mL vs 1.58×103 copies/mL; P = .020).Conclusion:Air dispersal of common respiratory viruses may have infection prevention and public health implications. |
| تدمد: | 1559-6834 0899-823X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc9d63f47a5eb2ffb2586d46c259111Test https://doi.org/10.1017/ice.2022.186Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3cc9d63f47a5eb2ffb2586d46c259111 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15596834 0899823X |
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