دورية أكاديمية

Escherichia colishedding patterns in humans and dogs: insights into within-household transmission of phylotypes associated with urinary tract infections

التفاصيل البيبلوغرافية
العنوان: Escherichia colishedding patterns in humans and dogs: insights into within-household transmission of phylotypes associated with urinary tract infections
المؤلفون: DAMBORG, P., NIELSEN, S. S., GUARDABASSI, L.
المصدر: Epidemiology and Infection ; volume 137, issue 10, page 1457-1464 ; ISSN 0950-2688 1469-4409
بيانات النشر: Cambridge University Press (CUP)
سنة النشر: 2009
مصطلحات موضوعية: Infectious Diseases, Epidemiology
الوصف: SUMMARY Within-household transmission of Escherichia coli may contribute to the pathogenesis of urinary tract infection but understanding of transmission is limited by the lack of longitudinal data on individual shedding patterns. In this study, faecal E. coli was isolated over 6 months from 18 humans and 13 dogs in eight households. Typing 322 E. coli isolates by amplified fragment length polymorphism showed high overall diversity as indicated by the average diversity index (0·66). However, individual shedding patterns varied considerably: two persons carried a single resident E. coli clone throughout the study whereas distinct clones were isolated from other individuals on each sampling time. Nineteen clones were shared within six of the eight households and seven of these clones were shared between humans and dogs. The frequent sharing of clones belonging to phylotypes B2 ( n =7) or D ( n =4) supports the hypothesis that urovirulent E. coli are transmitted between household members, including dogs, or may be acquired by a common source such as food.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1017/s095026880900226x
الإتاحة: https://doi.org/10.1017/s095026880900226xTest
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S095026880900226XTest
حقوق: https://www.cambridge.org/core/termsTest
رقم الانضمام: edsbas.6F6E6E91
قاعدة البيانات: BASE