North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study
| العنوان: | North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study |
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| المؤلفون: | Maria Luisa Redondo, Paolo Vineis, Kim Overvad, Martine M. Ros, Simone J. P. M. Eussen, Per Magne Ueland, Marie-Christine Boutron-Ruault, Valentina Gallo, Øivind Midttun, J Schneede, H. Bas Bueno-de-Mesquita, Antonia Trichopoulou, Sabina Sieri, Emily Sonestedt, Rosario Tumino, Arve Ulvik, María Dolores Chirlaque, Teresa Norat, Klaus Meyer, Åse Fredriksen, Petra H.M. Peeters, Eva Ardanaz, Laure Dossus, Steinar Hustad, Florence Perquier, Birgit Teucher, Elio Riboli, Roy Miodini Nilsen, Paul Brennan, Maria Santucci de Magistris, George Adarakis, Maria Plada, Bethany Van Guelpen, Ulrika Ericson, Noortje IJssennagger, Mattias Johansson, Shu Chun Chuang, Petra A. Wark, Verena A. Grote, Stein Emil Vollset, Raul Zamora-Ros |
| المساهمون: | Epidemiologie, RS: CARIM School for Cardiovascular Diseases |
| المصدر: | British Journal of Nutrition, 110, 363-74 British Journal of Nutrition, 110, 2, pp. 363-74 British Journal of Nutrition 110 (2013) 2 British Journal of Nutrition, 110(2), 363-374 Eussen, S J P M, Nilsen, R M, Midttun, O, Hustad, S, Ijssennagger, N, Meyer, K, Fredriksen, A, Ulvik, A, Ueland, P M, Brennan, P, Johansson, M, Bueno-de-Mesquita, B, Vineis, P, Chuang, S-C, Boutron-Ruault, M C, Dossus, L, Perquier, F, Overvad, K, Teucher, B, Grote, V A, Trichopoulou, A, Adarakis, G, Plada, M, Sieri, S, Tumino, R, de Magistris, M S, Ros, M M, Peeters, P H M, Redondo, M L, Zamora-Ros, R, Chirlaque, M-D, Ardanaz, E, Sonestedt, E, Ericson, U, Schneede, J, van Guelpen, B, Wark, P A, Gallo, V, Norat, T, Riboli, E & Vollset, S E 2013, ' North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe : results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study ', British Journal of Nutrition, vol. 110, no. 2, pp. 363-74 . https://doi.org/10.1017/S0007114512004990Test British Journal of Nutrition; 110(2), pp 363-374 (2013) British Journal of Nutrition, 110(2), 363-374. Cambridge University Press |
| بيانات النشر: | Cambridge University Press, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Male, Nutrition and Disease, 030309 nutrition & dietetics, Health Behavior, Medicine (miscellaneous), homocysteine metabolism, chemistry.chemical_compound, 0302 clinical medicine, Voeding en Ziekte, Ethnicity, Serine, tandem mass-spectrometry, alcohol-consumption, 030212 general & internal medicine, Prospective Studies, 24-hour dietary recalls, Prospective cohort study, microbiological assay, dairy-products, 0303 health sciences, Nutrition and Dietetics, nutrient intake, Incidence (epidemiology), Smoking, Middle Aged, One-carbon metabolism, 3. Good health, European Prospective Investigation into Cancer and Nutrition, Europe, Vitamin B 12, Biochemistry, Cohort, Amino acids, Female, Vitamin, Adult, Alcohol Drinking, Glycine, Biology, Cobalamin, folate intake, 03 medical and health sciences, Folic Acid, Sex Factors, B-vitamins, Humans, Vitamin B12, Life Style, VLAG, Molecular epidemiology Aetiology, screening and detection [NCEBP 1], Aged, Global Nutrition, Wereldvoeding, colorectal-cancer, Sarcosine, B vitamins, chemistry, Chronic Disease, 10 countries, Demography |
| الوصف: | Different lifestyle patterns across Europe may influence plasma concentrations of B-vitamins and one-carbon metabolites and their relation to chronic disease. Comparison of published data on one-carbon metabolites in Western European regions is difficult due to differences in sampling procedures and analytical methods between studies. The present study aimed, to compare plasma concentrations of one-carbon metabolites in Western European regions with one laboratory performing all biochemical analyses. We performed the present study in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort among 5446 presumptively healthy individuals. Quantile regression was used to compare sex-specific median concentrations between Northern (Denmark and Sweden), Central (France, Germany, The Netherlands and United Kingdom) and Southern (Greece, Spain and Italy) European regions. The lowest folate concentrations were observed in Northern Europe (men, 10·4 nmol/l; women, 10·7 nmol/l) and highest concentrations in Central Europe. Cobalamin concentrations were slightly higher in Northern Europe (men, 330 pmol/l; women, 352 pmol/l) compared with Central and Southern Europe, but did not show a clear north–south gradient. Vitamin B2 concentrations were highest in Northern Europe (men, 22·2 nmol/l; women, 26·0 nmol/l) and decreased towards Southern Europe (Ptrend6 concentrations were highest in Central Europe in men (77·3 nmol/l) and highest in the North among women (70·4 nmol/l), with decreasing concentrations towards Southern Europe in women (Ptrend |
| وصف الملف: | application/pdf; application/octet-stream |
| اللغة: | English |
| تدمد: | 0007-1145 1475-2662 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5c97ab847c153b87c9a24d2b6dbbb8Test http://lup.lub.lu.se/record/3975715Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5b5c97ab847c153b87c9a24d2b6dbbb8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00071145 14752662 |
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