دورية أكاديمية
In vivo confocal microscopy in fungal keratitis
| العنوان: | In vivo confocal microscopy in fungal keratitis |
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| المؤلفون: | Brasnu, Emmanuelle, Bourcier, Tristan, Dupas, Bénédicte, Degorge, Sandrine, Rodallec, Thibault, Laroche, Laurent, Borderie, Vincent, Baudouin, Christophe |
| بيانات النشر: | British Medical Journal Publishing Group |
| سنة النشر: | 2007 |
| المجموعة: | HighWire Press (Stanford University) |
| مصطلحات موضوعية: | Clinical science - Scientific reports |
| الوصف: | Background: Fungal keratitis is a major blinding eye disease found throughout the world, particularly in developing countries. Given the recent increase in Fusarium keratitis infections in contact lens wearers owing to contact lens solutions, a warning was recently issued by the Food and Drug Administration, making it a public health concern in developed countries. Objective: To show the advantages of in vivo confocal microscopy imaging using the Heidelberg Retina Tomograph II-Rostock Cornea Module (HRTII-RCM) in the early diagnosis of fungal keratitis. Methods: HRTII-RCM confocal microscopy was performed on five patients presenting with fungal keratitis and on three donor corneas contaminated with Fusarium solani , Aspergillus fumigatus and Candida albicans . Results: Direct microscopic evaluation of corneal smears and culture revealed the presence of F solani in four cases and C albicans in one case. HRTII-RCM examination of the infected patients and contaminated donor corneas revealed numerous high-contrast elements resembling Fusarium , Aspergillus hyphae or Candida pseudofilaments in the anterior stroma. Conclusion: HRTII-RCM in vivo confocal microscopy is a new, non-invasive and rapid technique for the early diagnosis of fungal keratitis, showing high-resolution images resembling fungal structures in the early phase of the disease. |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | http://bjo.bmj.com/cgi/content/short/91/5/588Test; http://dx.doi.org/10.1136/bjo.2006.107243Test |
| DOI: | 10.1136/bjo.2006.107243 |
| الإتاحة: | https://doi.org/10.1136/bjo.2006.107243Test http://bjo.bmj.com/cgi/content/short/91/5/588Test |
| حقوق: | Copyright (C) 2007, BMJ Publishing Group Ltd |
| رقم الانضمام: | edsbas.A69A3DDC |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/bjo.2006.107243 |
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