Brain charts for the human lifespan
| العنوان: | Brain charts for the human lifespan |
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| المؤلفون: | Adamson C, Adler S, Alexander-Bloch AF, Alexopoulos GS, Anagnostou E, Anderson KM, Areces-Gonzalez A, Astle DE, Auyeung B, Ayub M, Bae J, Ball G, Baron-Cohen S, Beare R, Bedford SA, Benegal V, Bethlehem RAI, Beyer F, Binette AP, Blangero J, Boardman JP, Borzage M, Bosch-Bayard JF, Bourke N, Bullmore ET, Cabez MB, Calhoun VD, Chakravarty MM, Chen C, Chertavian C, Chetelat G, Chong YS, Cole JH, Corvin A, Costantino M, Courchesne E, Crivello F, Cropley VL, Crosbie J, Crossley N, Delarue M, Delorme R, Desrivieres S, Devenyi GA, Di Biase MA, Dolan R, Donald KA, Donohoe G, Dunlop K, Edwards AD, Elison JT, Ellis CT, Elman JA, Eyler L, Fair DA, Feczko E, Fletcher PC, Fonagy P, Franz CE, Galan-Garcia L, Gholipour A, Giedd J, Gilmore JH, Glahn DC, Goodyer IM, Grant PE, Groenewold NA, Gunning FM, Gur RC, Gur RE, Hammill CF, Hansson O, Hedden T, Heinz A, Henson RN, Heuer K, Hoare J, Holla B, Holmes AJ, Holt R, Huang H, Im K, Ipser J, Jack CR, Jackowski AP, Jia T, Johnson KA, Jones DT, Jones PB, Kahn RS, Karlsson Hasse, Karlsson Linda, Kawashima R, Kelley EA, Kern S, Kim KW, Kitzbichler MG, Kremen WS, Lalonde F, Landeau B, Lee S, Lerch J, Lewis JD, Li J, Liao W, Liston C, Lombardo MV, Lv J, Lynch C, Mallard TT, Marcelis M, Markello RD, Mathias SR, Mazoyer B, McGuire P, Meaney MJ, Mechelli A, Medic N, Misic B, Morgan SE, Mothersill D, Nigg J, Ong MQW, Ortinau C, Ossenkoppele R, Ouyang M, Palaniyappan L, Paly L, Pan PM, Pantelis C, Park MM, Paus T, Pausova Z, Paz-Linares D, Pierce K, Qian X, Qiu A, Qiu J, Raznahan A, Rittman T, Rodrigue A, Rollins CK, Romero-Garcia R, Ronan L, Rosenberg MD, Rowitch DH, Salum GA, Satterthwaite TD, Schaare HL, Schachar RJ, Scholl M, Schultz AP, Schumann G, Seidlitz J, Sharp D, Shinohara RT, Skoog I, Smyser CD, Sperling RA, Stein DJ, Stolicyn A, Suckling J, Sullivan G, Taki Y, Thyreau B, Toro R, Traut N, Tsvetanov KA, Turk-Browne NB, Tuulari Jetro J, Tzourio C, Vachon-Presseau E, Valdes-Sosa MJ, Valdes-Sosa PA, Valk SL, Vandekar SN, Vasung L, Vertes PE, Victoria LW, Villeneuve S, Villringer A, Vogel JW, Wagstyl K, Wang YS, Warfield SK, Warrier V, Westman E, Westwater ML, Whalley HC, White SR, Witte AV, Yang N, Yeo B, Yun H, Zalesky A, Zar HJ, Zettergren A, Zhou JH, Ziauddeen H, Zugman A, Zuo XN, van Amelsvoort T |
| المساهمون: | kliinisen laitoksen yhteiset, Department of Clinical Medicine, psykiatria, Psychiatry, tyks, vsshp, tyks, vsshp, väestötutkimuskeskus, Centre for Population Health Research (POP Centre), 2607008, 2607300, 2607316 |
| بيانات النشر: | SPRINGER NATURE United Kingdom Britannia GB |
| سنة النشر: | 2022 |
| المجموعة: | University of Turku: UTUPub / Turun yliopisto |
| الوصف: | Over the past few decades, neuroimaging has become a ubiquitoustool in basic research and clinical studies of the human brain. However, no reference standards currently exist to quantify individual differences in neuroimaging metrics overtime, in contrast to growth charts for anthropometric traits such as height and weight. Here we assemble an interactive open resource to benchmark brain morphology derived from any current or future sample of MRI data (http://www.brainchart.ioTest/). With the goal of basing these reference charts on the largest and most inclusive dataset available, acknowledging limitations due to known biases of MRI studies relative to the diversity of the global population, we aggregated 123,984 MRI scans, across more than 100 primary studies, from 101,457 human participants between 115 days post-conception to 100 years of age. MRI metrics were quantified by centile scores, relative to non-linear trajectories of brain structural changes, and rates of change, over the lifespan. Brain charts identified previously unreported neurodevelopmental milestones, showed high stability of individuals across longitudinal assessments, and demonstrated robustness to technical and methodological differences between primary studies. Centile scores showed increased heritability compared with non-centiled MRI phenotypes, and provided a standardized measure of atypical brain structure that revealed patterns of neuroanatomical variation across neurological and psychiatric disorders. In summary, brain charts are an essential step towards robust quantification of individual variation benchmarked to normative trajectories in multiple, commonly used neuroimaging phenotypes. |
| نوع الوثيقة: | other/unknown material |
| اللغة: | English |
| تدمد: | 1476-4687 0028-0836 |
| العلاقة: | 604; Nature; 7906; https://www.utupub.fi/handle/10024/156286Test; https://www.nature.com/articles/s41586-022-04554-yTest; URN:NBN:fi-fe2022081153707 |
| الإتاحة: | https://www.utupub.fi/handle/10024/156286Test https://www.nature.com/articles/s41586-022-04554-yTest |
| رقم الانضمام: | edsbas.46F62AD0 |
| قاعدة البيانات: | BASE |
| تدمد: | 14764687 00280836 |
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