دورية أكاديمية
Assessment of ALK gene rearrangement in lung cancer using a new rapid automated SureFISH (Dako Omnis) assay
| العنوان: | Assessment of ALK gene rearrangement in lung cancer using a new rapid automated SureFISH (Dako Omnis) assay |
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| المؤلفون: | Takeda, Maiko, Kasai, Takahiko, Shimizu, Shigeki, Kitaichi, Masanori, Kojima, Kensuke, Nagoya, Akihiro, Hayashi, Akio, Utsumi, Tomoki, Yoon, Hyung-Eun, Matsumura, Akihide, Atagi, Shinji |
| بيانات النشر: | BMJ Publishing Group Ltd |
| سنة النشر: | 2017 |
| المجموعة: | HighWire Press (Stanford University) |
| مصطلحات موضوعية: | Short report |
| الوصف: | The ALK fluorescence in situ hybridisation (FISH) method is the examination essential for pathological diagnosis and choice of molecular-targeted therapy in ALK -rearranged lung cancer. Here, for detection of ALK gene rearrangement in patients with lung cancer, we evaluated the rapid FISH technology ( ALK SureFISH), a newly developed assay for the automated staining platform Dako Omnis, using 21 formalin-fixed paraffin-embedded (FFPE) samples. All cases could be evaluated with the SureFISH method. SureFISH provided excellent quality signals without any background staining. The SureFISH assay was able to offer a rapid turnaround time (approximately 3.5 hours) and was 100% concordant with prior Vysis FISH results in our laboratory. |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | http://jcp.bmj.com/cgi/content/short/70/8/712Test; http://dx.doi.org/10.1136/jclinpath-2016-204311Test |
| DOI: | 10.1136/jclinpath-2016-204311 |
| الإتاحة: | https://doi.org/10.1136/jclinpath-2016-204311Test http://jcp.bmj.com/cgi/content/short/70/8/712Test |
| حقوق: | Copyright (C) 2017, BMJ Publishing Group |
| رقم الانضمام: | edsbas.105ABCDC |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/jclinpath-2016-204311 |
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