دورية أكاديمية

Living-donor lobar lung transplantation from a hepatitis B surface antigen-positive donor to a negative recipient.

التفاصيل البيبلوغرافية
العنوان: Living-donor lobar lung transplantation from a hepatitis B surface antigen-positive donor to a negative recipient.
المؤلفون: Takafumi Yamaya, Masaaki Sato, Chihiro Konoeda, Jun Nakajima
المصدر: BMJ Case Reports; Oct2023, Vol. 16 Issue 10, p1-5, 5p
مستخلص: A man in his 40s was diagnosed with interstitial pneumonia at another hospital. He was referred to our hospital for lung transplantation. His lung function was rapidly declining, necessitating semiurgent livingdonor lobar lung transplantation (LDLLT). Although he was negative for hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (HBsAb), one of the candidate donors was proven HBsAg-positive. The risk of hepatitis B virus (HBV) infection at transplantation was considered high; however, after careful discussion about the safety of the recipient and donor, it was decided to conduct LDLLT. For prophylaxis, human anti-HBV surface immunoglobulin and entecavir were administered to the recipient. HBsAg and HBsAb were continuously monitored postoperatively and consistently negative, suggesting no signs of reactivation in the recipient, even after corticosteroid pulse treatment for acute cellular rejection. More than 6 months after LDLLT, there were no signs of HBV reactivation in either the recipient or donor. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:1757790X
DOI:10.1136/bcr-2023-255663