دورية أكاديمية
Linguistic profile automated characterisation in pluripotential clinical high-risk mental state (CHARMS) conditions: methodology of a multicentre observational study
| العنوان: | Linguistic profile automated characterisation in pluripotential clinical high-risk mental state (CHARMS) conditions: methodology of a multicentre observational study |
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| المؤلفون: | Magnani, Luca, Carmisciano, Luca, dell’Orletta, Felice, Bettinardi, Ornella, Chiesa, Silvia, Imbesi, Massimiliano, Limonta, Giuliano, Montagna, Elisa, Turone, Ilaria, Martinasso, Dario, Aguglia, Andrea, Serafini, Gianluca, Amore, Mario, Costanza, Alessandra, Sibilla, Francesca, Calcagno, Pietro, Patti, Sara, Molino, Gabriella, Escelsior, Andrea, Trabucco, Alice, Marzano, Lisa, Brunato, Dominique, Ravelli, Andrea Amelio, Cappucciati, Marco, Fiocchi, Roberta, Guerzoni, Gisella, Maravita, Davide, Macchetti, Fabio, Mori, Elisa, Paglia, Chiara Anna, Roscigno, Federica, Saginario, Antonio |
| بيانات النشر: | BMJ Publishing Group |
| سنة النشر: | 2023 |
| المجموعة: | Middlesex University London: Research Repository |
| الوصف: | Introduction: Language is usually considered the social vehicle of thought in intersubjective communications. However, the relationship between language and high- order cognition seems to evade this canonical and unidirectional description (ie, the notion of language as a simple means of thought communication). In recent years, clinical high at-risk mental state (CHARMS) criteria (evolved from the Ultra-High-Risk paradigm) and the introduction of the Clinical Staging system have been proposed to address the dynamicity of early psychopathology. At the same time, natural language processing (NLP) techniques have greatly evolved and have been successfully applied to investigate different neuropsychiatric conditions. The combination of at-risk mental state paradigm, clinical staging system and automated NLP methods, the latter applied on spoken language transcripts, could represent a useful and convenient approach to the problem of early psychopathological distress within a transdiagnostic risk paradigm. Methods and analysis: Help-seeking young people presenting psychological distress (CHARMS+/− and Clinical Stage 1a or 1b; target sample size for both groups n=90) will be assessed through several psychometric tools and multiple speech analyses during an observational period of 1-year, in the context of an Italian multicentric study. Subjects will be enrolled in different contexts: Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), Section of Psychiatry, University of Genoa—IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Mental Health Department—territorial mental services (ASL 3—Genoa), Genoa, Italy; and Mental Health Department—territorial mental services (AUSL—Piacenza), Piacenza, Italy. The conversion rate to full-blown psychopathology (CS 2) will be evaluated over 2 years of clinical observation, to further confirm the predictive and discriminative value of CHARMS criteria and to verify the possibility of enriching them with several linguistic ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | https://eprints.mdx.ac.uk/37659/1/Magnani%20et%20al.BMJ066642.full%5B91%5D.pdfTest; Magnani, Luca , Carmisciano, Luca , dell’Orletta, Felice , Bettinardi, Ornella , Chiesa, Silvia , Imbesi, Massimiliano , Limonta, Giuliano , Montagna, Elisa , Turone, Ilaria , Martinasso, Dario , Aguglia, Andrea , Serafini, Gianluca , Amore, Mario , Costanza, Alessandra ORCID logoorcid:0000-0001-6387-6462 , Sibilla, Francesca , Calcagno, Pietro , Patti, Sara , Molino, Gabriella , Escelsior, Andrea , Trabucco, Alice , Marzano, Lisa ORCID logoorcid:0000-0001-9735-3512 , Brunato, Dominique , Ravelli, Andrea Amelio , Cappucciati, Marco , Fiocchi, Roberta , Guerzoni, Gisella , Maravita, Davide , Macchetti, Fabio , Mori, Elisa , Paglia, Chiara Anna , Roscigno, Federica and Saginario, Antonio (2023) Linguistic profile automated characterisation in pluripotential clinical high-risk mental state (CHARMS) conditions: methodology of a multicentre observational study. BMJ Open , 13 , e066642. ISSN 2044-6055 [Article] (doi:10.1136/bmjopen-2022-066642 ) |
| DOI: | 10.1136/bmjopen-2022-066642 |
| الإتاحة: | https://doi.org/10.1136/bmjopen-2022-066642Test https://eprints.mdx.ac.uk/37659Test/ https://eprints.mdx.ac.uk/37659/1/Magnani%20et%20al.BMJ066642.full%5B91%5D.pdfTest |
| حقوق: | cc_by_nc_4 |
| رقم الانضمام: | edsbas.7394FF0B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/bmjopen-2022-066642 |
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