دورية أكاديمية
Hospital end-of-life care in haematological malignancies
| العنوان: | Hospital end-of-life care in haematological malignancies |
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| المؤلفون: | Beaussant, Yvan, Daguindau, Etienne, Chauchet, Adrien, Rochigneux, Philippe, Tournigand, Christophe, Aubry, Régis, Morin, Lucas |
| المساهمون: | Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098) (RIGHT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang Bourgogne-Franche-Comté (EFS BFC)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC), Service d'hématologie, Institut Paoli-Calmettes (IPC), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes (IPC), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of California Los Angeles (UCLA), University of California (UC), Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Aging Research Center Karolinska Institutet (ARC ), Stockholm University-Karolinska Institutet Stockholm |
| المصدر: | ISSN: 2045-435X. |
| بيانات النشر: | HAL CCSD BMJ Publishing Group |
| سنة النشر: | 2018 |
| المجموعة: | Université de Franche-Comté (UFC): HAL |
| مصطلحات موضوعية: | [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Objective To investigate patterns of care during the last months of life of hospitalised patients who died from different haematological malignancies. Methods Nationwide register-based study, including all hospitalised adults ≥20 years who died from haematological malignancies in France in 2010–2013. Outcomes included use of invasive cancer treatments and referral to palliative care. Percentages are adjusted for sex and age using direct standardisation. Results Of 46 629 inpatients who died with haematological malignancies, 24.5% received chemotherapy during the last month before death, 48.5% received blood transfusion, 12.3% were under invasive ventilation and 18.1% died in intensive care units. We found important variations between haematological malignancies. The use of chemotherapy during the last month of life varied from 8.6% among patients with chronic myeloid leukaemia up to 30.1% among those with non-Hodgkin’s lymphoma (P<0.001). Invasive ventilation was used in 10.2% of patients with acute leukaemia but in 19.0% of patients with Hodgkin’s lymphoma (P<0.001). Palliative status was reported 30 days before death in only 14.8% of patients, and at time of death in 46.9% of cases. Overall, 5.5% of haematology patients died in palliative care units. Conclusion A high proportion of patients who died from haematological malignancies receive specific treatments near the end of life. There is a need for a better and earlier integration of the palliative care approach in the standard practice of haematology. However, substantial variation according to the type of haematological malignancy suggests that the patients should not be considered as one homogeneous group. Implementation of palliative care should account for differences across haematological malignancies. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-03689944; https://amu.hal.science/hal-03689944Test |
| DOI: | 10.1136/bmjspcare-2017-001446 |
| الإتاحة: | https://doi.org/10.1136/bmjspcare-2017-001446Test https://amu.hal.science/hal-03689944Test |
| رقم الانضمام: | edsbas.430DB008 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/bmjspcare-2017-001446 |
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