التفاصيل البيبلوغرافية
| العنوان: |
Electrical stimulation for seizure induction during SEEG exploration: a useful predictor of postoperative seizure recurrence? |
| المؤلفون: |
Trebuchon, Agnes, Racila, Renata, Cardinale, Francesco, Lagarde, Stanislas, McGonigal, Aileen, Lo Russo, Giorgio, Scavarda, Didier, Carron, Romain, Mai, Roberto, Chauvel, Patrick, Bartolomei, Fabrice, Francione, Stefano |
| المساهمون: |
VIBRATIONS, AMIDEX project |
| المصدر: |
Journal of Neurology, Neurosurgery & Psychiatry ; volume 92, issue 1, page 22-26 ; ISSN 0022-3050 1468-330X |
| بيانات النشر: |
BMJ |
| سنة النشر: |
2020 |
| مصطلحات موضوعية: |
Psychiatry and Mental health, Neurology (clinical), Surgery |
| الوصف: |
Objective Direct electrical stimulations of cerebral cortex are a traditional part of stereoelectroencephalography (SEEG) practice, but their value as a predictive factor for seizure outcome has never been carefully investigated. Patients and method We retrospectively analysed a cohort of 346 patients operated on for drug-resistant focal epilepsy after SEEG exploration. As potential predictors we included: aetiology, MRI data, age of onset, duration of epilepsy, age at surgery, topography of surgery and whether a seizure was induced by either low frequency electrical stimulation (LFS) or high frequency electrical stimulation. Results Of 346 patients, 63.6% had good outcome (no seizure recurrence, Engel I). Univariate analysis demonstrated significant correlation with favourable outcome (Engel I) for: aetiology, positive MRI and seizure induced by stimulation. At multivariate analysis, informative MRI, type II focal cortical dysplasia and tumour reduced the risk of seizure recurrence (SR) by 47%, 58% and 81%, respectively. Compared with the absence of induced seizures, the occurrence of ictal events after LFS significantly predicts a favourable outcome on seizures, with only 44% chance of disabling SR at last follow-up. Conclusion Among the already known predictors outcome, seizure induction by LFS therefore represents a positive predictive factor for seizure outcome after surgery. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1136/jnnp-2019-322469 |
| الإتاحة: |
https://doi.org/10.1136/jnnp-2019-322469Test |
| رقم الانضمام: |
edsbas.7CE69E04 |
| قاعدة البيانات: |
BASE |
