التفاصيل البيبلوغرافية
| العنوان: |
New approach to testing treatments for osteoarthritis: FastOA |
| المؤلفون: |
Felson, David, Lotz, Martin K, Jin, Yuxuan, Jones, Morgan, Kim, Jason S, Spindler, Kurt |
| المساهمون: |
Arthritis Foundation, National Institutes of Health |
| المصدر: |
Annals of the Rheumatic Diseases ; volume 83, issue 3, page 274-276 ; ISSN 0003-4967 1468-2060 |
| بيانات النشر: |
BMJ |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
General Biochemistry, Genetics and Molecular Biology, Immunology, Immunology and Allergy, Rheumatology |
| الوصف: |
Animal models of post traumatic osteoarthritis have shown many promising treatments for disease, but human trials have mostly failed to identify effective treatments. This viewpoint suggests that the frequent failure of drug and treatment development in osteoarthritis is due, in part, to the advanced stage of disease of patients in trials and suggests that mirroring the animal model approach might be more successful. It suggests a path forward by enriching trial enrollees with those likely to develop post traumatic OA quickly. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1136/ard-2023-224675 |
| الإتاحة: |
https://doi.org/10.1136/ard-2023-224675Test |
| رقم الانضمام: |
edsbas.A63CEE3B |
| قاعدة البيانات: |
BASE |
