التفاصيل البيبلوغرافية
| العنوان: |
P-022 Treating symptomatic intracranial atherosclerosis with the balloon expandable Pharos Vitesse neurovascular stent: initial experience |
| المؤلفون: |
Wakhloo, A, Patel, N, Thors, A, Duhamel, E, Morris, J, Ramzan, M, Moonis, M, Gounis, M |
| المصدر: |
Journal of NeuroInterventional Surgery ; volume 2, issue Suppl 1, page A25-A25 ; ISSN 1759-8478 1759-8486 |
| بيانات النشر: |
BMJ |
| سنة النشر: |
2010 |
| الوصف: |
Purpose To describe our early experience with the balloon expandable Pharos Vitesse stent for symptomatic, high grade intracranial stenosis. Materials and methods Our center has enrolled five patients to date in the VISSIT (Vitesse Intracranial Stent Study for Ischemic Therapy) Trial.1 This prospective, multicenter, randomized trial is designed to compare best medical therapy alone to best medical therapy plus stenting for symptomatic, high grade intracranial stenosis. In conformance with the study design, patients were treated for 70–80% stenosis (inclusion criterion 70–99%) of the intracranial internal carotid, middle cerebral or intradural vertebral arteries. The patients ranged from 49 to 76 years of age (mean 63). There were four men and one woman. All target lesions and vessels were of appropriate size for treatment using the Pharos Vitesse stent. All patients underwent neurological assessment, including evaluation of the modified Rankin Scale (mRS) and CT studies prior to diagnostic digital subtraction angiography (DSA). Four patients also underwent CT perfusion (CTP). After diagnostic DSA, three patients were randomized to the stenting arm of the trial. One patient who was randomized to the medical therapy arm failed medical therapy and underwent stenting after recurrent ischemic stroke in the territory of the stenotic vessel. After stenting, mRS and CTP were performed in all patients prior to discharge. Results Stenting was technically successful in all cases. In three cases, there was no residual stenosis. In one case, heavily calcified, concentric atherosclerotic plaque resulted in residual stenosis of 30%. There were no procedural complications. One patient recovered from anesthesia with neurologic deficits localizable to the treated territory. These resolved completely and spontaneously within 24 h. No other periprocedural neurological adverse events were encountered. Two of three patients undergoing stenting had abnormal CTP findings in the territory distal to the stenotic lesion. In one, MTT was ... |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1136/jnis.2010.003236.22 |
| الإتاحة: |
https://doi.org/10.1136/jnis.2010.003236.22Test |
| رقم الانضمام: |
edsbas.5ACF9401 |
| قاعدة البيانات: |
BASE |
