Re-emergence of tularemia in Germany: Presence of Francisella tularensis in different rodent species in endemic areas
| العنوان: | Re-emergence of tularemia in Germany: Presence of Francisella tularensis in different rodent species in endemic areas |
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| المؤلفون: | Kerstin Mätz-Rensing, Wolf D. Splettstoesser, Erik Seibold, Philipp Kaysser, M. Pfeffer, Sandra Essbauer |
| المصدر: | BMC Infectious Diseases, Vol 8, Iss 1, p 157 (2008) BMC Infectious Diseases |
| بيانات النشر: | BMC, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Disease reservoir, Endemic Diseases, Rodent, 599.8, 030231 tropical medicine, Zoology, Rodentia, Disease Outbreaks, Serology, Microbiology, lcsh:Infectious and parasitic diseases, Tularemia, 03 medical and health sciences, Ticks, 0302 clinical medicine, Recurrence, Germany, biology.animal, medicine, Animals, Humans, lcsh:RC109-216, Francisella tularensis, Disease Reservoirs, 0303 health sciences, biology, 030306 microbiology, Outbreak, bacterial infections and mycoses, biology.organism_classification, medicine.disease, Infectious Diseases, Parasitology, Siphonaptera, Francisella, Water Microbiology, Research Article |
| الوصف: | Background Tularemia re-emerged in Germany starting in 2004 (with 39 human cases from 2004 to 2007) after over 40 years of only sporadic human infections. The reasons for this rise in case numbers are unknown as is the possible reservoir of the etiologic agent Francisella (F.) tularensis. No systematic study on the reservoir situation of F. tularensis has been published for Germany so far. Methods We investigated three areas six to ten months after the initial tularemia outbreaks for the presence of F. tularensis among small mammals, ticks/fleas and water. The investigations consisted of animal live-trapping, serologic testing, screening by real-time-PCR and cultivation. Results A total of 386 small mammals were trapped. F. tularensis was detected in five different rodent species with carrier rates of 2.04, 6.94 and 10.87% per trapping area. None of the ticks or fleas (n = 432) tested positive for F. tularensis. We were able to demonstrate F. tularensis-specific DNA in one of 28 water samples taken in one of the outbreak areas. Conclusion The findings of our study stress the need for long-term surveillance of natural foci in order to get a better understanding of the reasons for the temporal and spatial patterns of tularemia in Germany. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1471-2334 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357459a9053fd1a2935aeb035904f161Test http://www.biomedcentral.com/1471-2334/8/157Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....357459a9053fd1a2935aeb035904f161 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14712334 |
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