A scoping review of indirect comparison methods and applications using individual patient data
| العنوان: | A scoping review of indirect comparison methods and applications using individual patient data |
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| المؤلفون: | Meghan J. Elliott, Areti Angeliki Veroniki, Charlene Soobiah, Andrea C. Tricco, Sharon E. Straus |
| المصدر: | BMC Medical Research Methodology, Vol 16, Iss 1, Pp 1-14 (2016) BMC Medical Research Methodology |
| بيانات النشر: | BMC, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Research Report, Biomedical Research, Epidemiology, NETWORK METAANALYSIS, Cochrane Library, computer.software_genre, GUANFACINE EXTENDED-RELEASE, 0302 clinical medicine, Statistics, Medicine, Multiple treatments meta-analysis, 030212 general & internal medicine, Network meta-analysis, education.field_of_study, lcsh:R5-920, ATTENTION-DEFICIT/HYPERACTIVITY DISORDER, 030503 health policy & services, Individual participant data, TREATMENT COMPARISON METAANALYSIS, Hospital Records, 3. Good health, MULTIPLE TREATMENT COMPARISONS, 1117 Public Health And Health Services, Research Design, PUBLISHED SYSTEMATIC REVIEWS, Data mining, 0305 other medical science, lcsh:Medicine (General), Life Sciences & Biomedicine, Research Article, Scoping review, Patient Identification Systems, Matching (statistics), Population, MEDLINE, Health Informatics, CINAHL, 03 medical and health sciences, Meta-Analysis as Topic, General & Internal Medicine, Humans, MIXED TREATMENT COMPARISONS, education, Protocol (science), Science & Technology, Information Dissemination, business.industry, Reproducibility of Results, Patient-level data, Patient data, RANDOMIZED-TRIALS, PARTICIPANT DATA, Indirect comparison, Knowledge synthesis, Health Care Sciences & Services, ADJUSTED INDIRECT COMPARISONS, business, computer, Research methods |
| الوصف: | Background Several indirect comparison methods, including network meta-analyses (NMAs), using individual patient data (IPD) have been developed to synthesize evidence from a network of trials. Although IPD indirect comparisons are published with increasing frequency in health care literature, there is no guidance on selecting the appropriate methodology and on reporting the methods and results. Methods In this paper we examine the methods and reporting of indirect comparison methods using IPD. We searched MEDLINE, Embase, the Cochrane Library, and CINAHL from inception until October 2014. We included published and unpublished studies reporting a method, application, or review of indirect comparisons using IPD and at least three interventions. Results We identified 37 papers, including a total of 33 empirical networks. Of these, only 9 (27 %) IPD-NMAs reported the existence of a study protocol, whereas 3 (9 %) studies mentioned that protocols existed without providing a reference. The 33 empirical networks included 24 (73 %) IPD-NMAs and 9 (27 %) matching adjusted indirect comparisons (MAICs). Of the 21 (64 %) networks with at least one closed loop, 19 (90 %) were IPD-NMAs, 13 (68 %) of which evaluated the prerequisite consistency assumption, and only 5 (38 %) of the 13 IPD-NMAs used statistical approaches. The median number of trials included per network was 10 (IQR 4–19) (IPD-NMA: 15 [IQR 8–20]; MAIC: 2 [IQR 3–5]), and the median number of IPD trials included in a network was 3 (IQR 1–9) (IPD-NMA: 6 [IQR 2–11]; MAIC: 2 [IQR 1–2]). Half of the networks (17; 52 %) applied Bayesian hierarchical models (14 one-stage, 1 two-stage, 1 used IPD as an informative prior, 1 unclear-stage), including either IPD alone or with aggregated data (AD). Models for dichotomous and continuous outcomes were available (IPD alone or combined with AD), as were models for time-to-event data (IPD combined with AD). Conclusions One in three indirect comparison methods modeling IPD adjusted results from different trials to estimate effects as if they had come from the same, randomized, population. Key methodological and reporting elements (e.g., evaluation of consistency, existence of study protocol) were often missing from an indirect comparison paper. Electronic supplementary material The online version of this article (doi:10.1186/s12874-016-0146-y) contains supplementary material, which is available to authorized users. |
| اللغة: | English |
| تدمد: | 1471-2288 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e053757a46ca93180ca611f74c35fcTest http://link.springer.com/article/10.1186/s12874-016-0146-yTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....99e053757a46ca93180ca611f74c35fc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14712288 |
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