An uncommon presentation of hyperhomocysteinemia and vitamin B12 deficiency: a case report
| العنوان: | An uncommon presentation of hyperhomocysteinemia and vitamin B12 deficiency: a case report |
|---|---|
| المؤلفون: | Sanjay D'Cruz, Vinay Kapur, Ravinder Kaur |
| المصدر: | Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-5 (2019) Journal of Medical Case Reports |
| بيانات النشر: | BMC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Glycerol, Male, Pediatrics, medicine.medical_specialty, Hyperhomocysteinemia, lcsh:Medicine, Case Report, 030204 cardiovascular system & hematology, Thrombophilia, 03 medical and health sciences, 0302 clinical medicine, Seizures, Venous thrombosis, medicine, Humans, Mannitol, Vitamin B12, Young adult, Pregnancy, Heparin, business.industry, Valproic Acid, lcsh:R, Anticoagulants, Brain, nutritional and metabolic diseases, Vitamin B 12 Deficiency, General Medicine, medicine.disease, Diuretics, Osmotic, Magnetic Resonance Imaging, Substance abuse, Vitamin B 12, 030220 oncology & carcinogenesis, Vitamin B Complex, Etiology, Anticonvulsants, Warfarin, Intracranial Thrombosis, business |
| الوصف: | Introduction Cerebral venous thrombosis is relatively rare and characterized by a wide spectrum of clinical features. It is more common in young adults with women affected more than men. The diagnosis of cerebral venous thrombosis is easier nowadays due to easy access to advanced neuroimaging techniques. Abnormalities in thrombophilic profile are associated with enhanced risk of cerebral venous thrombosis. It has varied etiologies such as hypercoagulable states, infection, dehydration, pregnancy, and substance abuse. Hyperhomocysteinemia is found to be closely associated with an enhanced risk of cerebral venous thrombosis. Case presentation Here we report a case of cerebral venous thrombosis secondary to hyperhomocysteinemia caused by vitamin B12 deficiency in a 32-year-old Indo-Aryan man. A detailed coagulation workup led us to find the etiology of cerebral venous thrombosis in this patient who followed a strict vegetarian diet and had vitamin B12 deficiency leading to hyperhomocysteinemia. Conclusion There are conflicting reports in the literature about the association of hyperhomocysteinemia, B12 deficiency, and cerebral venous thrombosis but some reports point to a significant association. We conclude that further studies with a large sample size are required to analyze the effect of hyperhomocysteinemia and low vitamin B12 on the risk of cerebral venous thrombosis. |
| اللغة: | English |
| تدمد: | 1752-1947 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c205f9ec37223ac1ed4d1474f98f37Test http://link.springer.com/article/10.1186/s13256-019-1988-9Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....77c205f9ec37223ac1ed4d1474f98f37 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17521947 |
|---|