Important risk factors and attributable risk of vertebral fractures in the population-based Tromsø study
| العنوان: | Important risk factors and attributable risk of vertebral fractures in the population-based Tromsø study |
|---|---|
| المؤلفون: | Svanhild Haugnes Waterloo, A.J. Søgaard, Bente Morseth, Tuan V. Nguyen, John A. Eisman, Nguyen D. Nguyen, Luai A. Ahmed, Nina Emaus |
| المصدر: | BMC Musculoskeletal Disorders, Vol 13, Iss 1, p 163 (2012) BMC Musculoskeletal Disorders |
| بيانات النشر: | BMC, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Questionnaires, Ryggvirvel, Male, lcsh:Diseases of the musculoskeletal system, Bone density, Cross-sectional study, Osteoporosis, Absorptiometry, Photon, Risk Factors, Bone Density, Surveys and Questionnaires, Odds Ratio, Prevalence, Medicine, Orthopedics and Sports Medicine, Aged, 80 and over, education.field_of_study, Lumbar Vertebrae, Norway, Population based study, Age Factors, Middle Aged, VDP::Medical disciplines: 700::Basic medical, dental and veterinary science disciplines: 710::Anatomy, physical anthropology: 717, medicine.anatomical_structure, Vertebral fractures, Spinal Fractures, Female, Hip Joint, Risikofaktorer, Risk assessment, Research Article, Adult, medicine.medical_specialty, Population, Lumbar vertebrae, Risk Assessment, Thoracic Vertebrae, Sex Factors, Rheumatology, Humans, Brudd, Osteoporose, education, Life Style, Aged, Chi-Square Distribution, Population attributable risk (par), VDP::Medisinske Fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710::Anatomi, fysisk antropologi: 717, business.industry, Morphometry, Odds ratio, medicine.disease, Orthopedics, Cross-Sectional Studies, Logistic Models, Risk factors, Multivariate Analysis, Attributable risk, Physical therapy, lcsh:RC925-935, business, Demography |
| الوصف: | This article is part of Svanhild H. Waterloo's doctoral thesis, available in Munin at http://hdl.handle.net/10037/5557Test Vertebral fractures, the most common type of osteoporotic fractures, are associated with increased risk of subsequent fracture, morbidity, and mortality. The aim of this study was to examine the contribution of important risk factors to the variability in vertebral fracture risk. Vertebral fracture was ascertained by VFA method (DXA, GE Lunar Prodigy) in 2887 men and women, aged between 38 and 87 years, in the population-based Tromsø Study 2007/2008. Bone mineral density (BMD; g/cm2) at the hip was measured by DXA. Lifestyle information was collected by questionnaires. Multivariable logistic regression model, with anthropometric and lifestyle factors included, was used to assess the association between each or combined risk factors and vertebral fracture risk. Population attributable risk was estimated for combined risk factors in the final multivariable model. In both sexes, age (odds ratio [OR] per 5 year increase: 1.32; 95% CI 1.19-1.45 in women and 1.21; 95% CI 1.10-1.33 in men) and BMD (OR per SD decrease: 1.60; 95% CI 1.34-1.90 in women and1.40; 95% CI 1.18-1.67 in men) were independent risk factors for vertebral fracture. At BMD levels higher than 0.85 g/cm2, men had a greater risk of fracture than women (OR 1.52; 95% CI 1.14-2.04), after adjusting for age. In women and men, respectively, approximately 46% and 33% of vertebral fracture risk was attributable to advancing age (more than 70 years) and low BMD (less than 0.85 g/cm2), with the latter having a greater effect than the former. These data confirm that age and BMD are major risk factors for vertebral fracture risk. However, in both sexes the two factors accounted for less than half of fracture risk. The identification of individuals with vertebral fracture is still a challenge. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1471-2474 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9408bf15cff01da8caa6b2f9c1e168Test http://www.biomedcentral.com/1471-2474/13/163Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ff9408bf15cff01da8caa6b2f9c1e168 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14712474 |
|---|