دورية أكاديمية
The impact of SARS-CoV2 vaccines on the incidence of graft versus host disease in allogeneic hematopoietic stem cell transplant recipients: a single-center retrospective study
| العنوان: | The impact of SARS-CoV2 vaccines on the incidence of graft versus host disease in allogeneic hematopoietic stem cell transplant recipients: a single-center retrospective study |
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| المؤلفون: | Dat Ngo, Jason Chen, Jose Tinajero, Ahmed Aribi, Shukaib Arslan, Guido Marcucci, Ryotaro Nakamura, Monzr M. Al Malki, Stephen J. Forman, Sanjeet Dadwal, Haris Ali |
| المصدر: | Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-5 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine (General) LCC:Biochemistry |
| مصطلحات موضوعية: | Severe acute respiratory syndrome coronavirus-2 (SARS-CoV2), COVID-19 vaccine, BNT162b2, mRNA-1273, Allogeneic hematopoietic stem cell transplantation, Graft-versus-host disease, Medicine (General), R5-920, Biochemistry, QD415-436 |
| الوصف: | Abstract This study reports the incidence of chronic graft versus host disease (GvHD) in allogeneic hematopoietic stem cell transplant (alloHCT) recipients who received SARS-CoV2 vaccination. The overall rates of new and worsening chronic GvHD combined were 14%, with median time from vaccination to GVHD being approximately three to four weeks. A majority of the cases were of mild to moderate severity and primarily localized to either the skin, mouth, or joints. Prior chronic GVHD and recent transplant were associated with higher GVHD rates following COVID-19 vaccination. More prospective studies are needed to provide a definitive mechanism for the impact of SARS-CoV2 vaccination on alloHCT patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1757-6512 |
| العلاقة: | https://doaj.org/toc/1757-6512Test |
| DOI: | 10.1186/s13287-023-03326-3 |
| الوصول الحر: | https://doaj.org/article/2e5cc911f7da42bf968ce978ae1ef0d8Test |
| رقم الانضمام: | edsdoj.2e5cc911f7da42bf968ce978ae1ef0d8 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17576512 |
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| DOI: | 10.1186/s13287-023-03326-3 |