دورية أكاديمية
Smoke, alcohol and drug addiction and female fertility
| العنوان: | Smoke, alcohol and drug addiction and female fertility |
|---|---|
| المؤلفون: | De Angelis C., Nardone A., Garifalos F., Pivonello C., Sansone A., Conforti A., Di Dato C., Sirico F., Alviggi C., Isidori A., Colao A., Pivonello R. |
| المساهمون: | De Angelis, C, Nardone, A, Garifalos, F, Pivonello, C, Sansone, A, Conforti, A, Di Dato, C, Sirico, F, Alviggi, C, Isidori, A, Colao, A, Pivonello, R |
| بيانات النشر: | BMC |
| سنة النشر: | 2020 |
| المجموعة: | Universitá degli Studi di Roma "Tor Vergata": ART - Archivio Istituzionale della Ricerca |
| مصطلحات موضوعية: | Alcohol, Drug, Endometriosis, Female Fertility, Ovary, Oviduct, PCOS, Reproduction, Smoke, Uterus, Alcohol Drinking, Animals, Female, Humans, Infertility, Polycystic Ovary Syndrome, Pregnancy, Smoking, Substance-Related Disorders, Settore MED/13 - ENDOCRINOLOGIA |
| الوصف: | Background Considerable interest has been gathered on the relevant impact of preventable factors, including incorrect lifestyle and unhealthy habits, on female fertility. Smoking, alcohol and addictive drugs consumption represent a major concern, given the broad range of diseases which might be favored or exacerbated by these dependable attitudes. Despite the well-characterized effects of prenatal exposure on pregnancy outcomes and fetus health, a substantial proportion of women of reproductive age is still concerned with these habits. At present, the impact of smoke, alcohol and addictive drugs on women fertility, and, particularly, the specific targets and underlying mechanisms, are still poorly understood or debated, mainly due to the scarcity of well-designed studies, and to numerous biases. Objective The current review will provide a comprehensive overview of clinical and experimental studies in humans and animals addressing the impact of smoke, alcohol and addictive drugs on female fertility, by also embracing effects on ovary, oviduct, and uterus, with particular reference to primary endpoints such as ovarian reserve, steroidogenesis, ovulation and menstrual cycle, oviduct function and uterus receptivity and implantation. A brief focus on polycystic ovary syndrome and endometriosis will be also included. Methods A Pubmed literature search was performed with selected keywords; articles were individually retrieved by each author. No limitation was set for publication date. Articles in languages other than English were excluded. Additional articles were retrieved from references list of selected manuscripts. Results and conclusions Currently, the most consistent evidences of a detrimental effect of smoke, alcohol and addictive drugs on specific domains of the female reproductive function are provided by experimental studies in animals. Overall, clinical studies suggest that smoking is associated to decreased fertility, although causal inference should be further demonstrated. Studies addressing the effect of ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/32164734; info:eu-repo/semantics/altIdentifier/wos/WOS:000519977800001; volume:18; issue:1; firstpage:21; journal:REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY; http://hdl.handle.net/2108/272657Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85081913028 |
| DOI: | 10.1186/s12958-020-0567-7 |
| الإتاحة: | https://doi.org/10.1186/s12958-020-0567-7Test http://hdl.handle.net/2108/272657Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.4B40E970 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s12958-020-0567-7 |
|---|