دورية أكاديمية
Nerve ultrasound as follow-up tool in treated multifocal motor neuropathy.
| العنوان: | Nerve ultrasound as follow-up tool in treated multifocal motor neuropathy. |
|---|---|
| المؤلفون: | Rattay, Tim, Winter, N., Décard, B. F., Dammeier, N. M., Härtig, F., Ceanga, M., Axer, H., Grimm, A. |
| المصدر: | European journal of neurology 24(9), 1125-1134 (2017). doi:10.1111/ene.13344 |
| بيانات النشر: | Blackwell Science78889 |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | info:eu-repo/classification/ddc/610, Action Potentials, Adult, Aged, Anatomy, Cross-Sectional, Carpal Tunnel Syndrome: diagnostic imaging, Carpal Tunnel Syndrome: drug therapy, Demyelinating Diseases: diagnostic imaging, Demyelinating Diseases: drug therapy, Electric Stimulation, Electrophysiological Phenomena, Female, Follow-Up Studies, Humans, Immunoglobulins, Intravenous: therapeutic use, Immunosuppressive Agents: therapeutic use, Longitudinal Studies, Male, Middle Aged, Motor Neuron Disease: diagnostic imaging, Motor Neuron Disease: drug therapy, Peripheral Nerves: diagnostic imaging, Ultrasonography, Intravenous, Immunosuppressive Agents |
| جغرافية الموضوع: | DE |
| الوصف: | High-resolution ultrasound is a valuable tool in supporting the diagnosis of multifocal motor neuropathy (MMN) but longitudinal data under therapy are lacking.The change in peripheral nerve ultrasound pattern in patients with MMN was assessed over time. Patients with MMN received a thorough initial examination and follow-up over a period of 6-12 months using high-resolution ultrasound of the cervical roots and the nerves of the arms and legs, nerve conduction studies, Medical Research Council Sum Score (MRCSS) and Rotterdam Inflammatory Neuropathy Cause and Treatment Group (INCAT) score to evaluate changes under treatment. The Ultrasound Pattern Sum Score (UPSS) was used as standardized peripheral nerve ultrasound protocol.Seventeen patients with MMN received initial examinations of whom 12 were successfully followed up. All patients with MMN showed at least localized but often multifocal peripheral nerve enlargement. An enlarged overall cross-sectional area as well as enlarged single fascicles (>3 mm²) in clinically and electrophysiologically affected (>90%) and unaffected (>70%) nerves were found. The UPSS did not correlate with clinical disability at both visits. However, the change in clinical disability (evaluated as difference in MRCSS) and the change in UPSS correlated significantly inversely (P = 0.004).High-resolution sonography of peripheral nerves revealed multifocal nerve enlargement in MMN. Distinct enlargement patterns may support the diagnosis. Ultrasound findings did not correlate well with clinical severity or electrophysiological findings at initial presentation. As changes in UPSS correlated significantly with the clinical course in terms of muscle strength (MRCSS), sonographic assessment may represent a useful tool for therapeutic monitoring. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/issn/1471-0552; info:eu-repo/semantics/altIdentifier/issn/1468-1331; info:eu-repo/semantics/altIdentifier/issn/1351-5101; info:eu-repo/semantics/altIdentifier/pmid/pmid:28681489; https://pub.dzne.de/record/139449Test; https://pub.dzne.de/search?p=id:%22DZNE-2020-05771%22Test |
| الإتاحة: | https://doi.org/10.1111/ene.13344Test https://pub.dzne.de/record/139449Test https://pub.dzne.de/search?p=id:%22DZNE-2020-05771%22Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.2AD1E954 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |