دورية أكاديمية

Perioperative and renal functional outcomes of elective robot-assisted partial nephrectomy (RAPN) for renal tumours with high surgical complexity

التفاصيل البيبلوغرافية
العنوان: Perioperative and renal functional outcomes of elective robot-assisted partial nephrectomy (RAPN) for renal tumours with high surgical complexity
المؤلفون: A. Volpe, D. Garrou, D. Amparore, G. D. Naeyer, F. Porpiglia, A. Mottrie, FICARRA, VINCENZO
المساهمون: A., Volpe, D., Garrou, D., Amparore, G. D., Naeyer, F., Porpiglia, Ficarra, Vincenzo, A., Mottrie
بيانات النشر: Blackwell Publishing Ltd
سنة النشر: 2013
المجموعة: Padua Research Archive (IRIS - Università degli Studi di Padova)
مصطلحات موضوعية: carcinoma, nephron-sparing surgery, outcome, PADUA score, renal cell, robotic partial nephrectomy
الوصف: ObjectiveTo evaluate the perioperative, postoperative and functional outcomes of robot-assisted partial nephrectomy (RAPN) for renal tumours with high surgical complexity at a large volume centre. Patients and MethodsPerioperative and functional outcomes of RAPNs for renal tumours with a Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score of 10 performed at our institution between September 2006 and December 2012 were collected in a prospectively maintained database and analysed. Surgical complications were graded according to the Clavien-Dindo classification. Serum creatinine and estimated glomerular filtration rate (eGFR) were assessed at the third postoperative day and 3-6 months after RAPN. ResultsIn all, 44 RAPNs for renal tumours with PADUA scores of 10 were included in the analysis; 23 tumours (52.3%) were cT1b. The median (interquartile range; range) operative time, estimated blood loss and warm ischaemia time (WIT) were 120 (94, 132; 60-230) min, 150 (80, 200; 25-1200) mL and 16 (13.8, 18; 5-35) min, respectively. Two intraoperative complications occurred (4.5%): one inferior vena caval injury and one bleed from the renal bed, which were both managed robotically. There were postoperative complications in 10 patients (22.7%), of whom four (9.1%) were high Clavien grade, including two bleeds that required percutaneous embolisation, one urinoma that resolved with ureteric stenting and one bowel occlusion managed with laparoscopic adhesiolysis. Two patients (4.5%) had positive surgical margins (PSMs) and were followed expectantly with no radiological recurrence at a mean follow-up of 23 months. The mean serum creatinine levels were significantly increased after surgery (121.1 vs 89.3mol/L; P = 0.001), but decreased over time, with no significant differences from the preoperative values at the 6-month follow-up (96.4 vs 89.3mol/L; P = 0.09). The same trend was seen for eGFR. ConclusionIn experienced hands RAPN for renal tumours with a PADUA score of 10 is feasible with short WIT, ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/24673750; info:eu-repo/semantics/altIdentifier/wos/WOS:000345341300022; volume:114; issue:6; firstpage:903; lastpage:909; numberofpages:7; journal:BJU INTERNATIONAL; http://hdl.handle.net/11577/3106722Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84905404796; http://www.scopus.com/inward/record.url?eid=2-s2.0-84905404796&partnerID=40&md5=63fc14d09cd6e13b5d434b66dfaec4b9Test
DOI: 10.1111/bju.12751
الإتاحة: https://doi.org/10.1111/bju.12751Test
http://hdl.handle.net/11577/3106722Test
http://www.scopus.com/inward/record.url?eid=2-s2.0-84905404796&partnerID=40&md5=63fc14d09cd6e13b5d434b66dfaec4b9Test
رقم الانضمام: edsbas.345320ED
قاعدة البيانات: BASE