دورية أكاديمية
No differences in mortality between users of pancreatic-specific and non-pancreatic-specific sulphonylureas: a cohort analysis
| العنوان: | No differences in mortality between users of pancreatic-specific and non-pancreatic-specific sulphonylureas: a cohort analysis |
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| المؤلفون: | Evans, Josie, Ogston, Simon A, Reimann, Frank, Gribble, Fiona M, Morris, Andrew D, Pearson, Ewan R |
| المساهمون: | Health Sciences Research - Stirling - LEGACY, University of Dundee, University of Cambridge, orcid:0000-0001-6672-7876 |
| بيانات النشر: | Blackwell Publishing |
| سنة النشر: | 2008 |
| المجموعة: | University of Stirling: Stirling Digital Research Repository |
| مصطلحات موضوعية: | Cardiovascular risk, Metformin, Sulphonylureas |
| الوصف: | To assess whether users of pancreatic-specific sulphonylureas are at reduced risk of mortality and cardiovascular mortality compared with users of non-specific sulphonylureas, we conducted a cohort study in the population of Tayside, Scotland. We identified 3331 patients with type 2 diabetes who were newly treated with sulphonylureas between 1994 and 2001 and categorized them into those treated with only pancreatic-specific sulphonylureas and those treated with only non-specific sulphonylureas. The risks of mortality and cardiovascular mortality were compared in a survival analysis. There were 2914 patients treated with pancreatic-specific sulphonylureas only, of which 683 (23.4%) died. Of 186 patients treated with non-specific drugs only, 40 (21.5%) died. After adjusting for confounding factors, the adjusted risk ratios (with 95% CI) for mortality and cardiovascular mortality were 0.84 (0.61 to 1.17) and 0.81 (0.59 to 1.11) among the non-specific users compared with the pancreatic-specific users. This provides no evidence that there are differences between the two sulphonylureas types. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Evans J, Ogston SA, Reimann F, Gribble FM, Morris AD & Pearson ER (2008) No differences in mortality between users of pancreatic-specific and non-pancreatic-specific sulphonylureas: a cohort analysis. Diabetes, Obesity and Metabolism, 10 (4), pp. 350-352. https://doi.org/10.1111/j.1463-1326.2007.00833.xTest; http://hdl.handle.net/1893/7509Test; WOS:000253885800010; 781293; http://dspace.stir.ac.uk/bitstream/1893/7509/1/Evans_2008_No_differences_in_mortality.pdfTest |
| DOI: | 10.1111/j.1463-1326.2007.00833.x |
| الإتاحة: | https://doi.org/10.1111/j.1463-1326.2007.00833.xTest http://hdl.handle.net/1893/7509Test http://dspace.stir.ac.uk/bitstream/1893/7509/1/Evans_2008_No_differences_in_mortality.pdfTest |
| حقوق: | The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. ; http://www.rioxx.net/licenses/under-embargo-all-rights-reservedTest ; 2999-12-18 ; [Evans_2008_No_differences_in_mortality.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work. |
| رقم الانضمام: | edsbas.9E5B0669 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/j.1463-1326.2007.00833.x |
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