التفاصيل البيبلوغرافية
| العنوان: |
Primary central nervous system angiosarcoma: two case reports |
| المؤلفون: |
Hackney, James R, Palmer, Cheryl, Riley, Kristen O, Cure, Joel K, Fathallah-Shaykh, Hassan M, Nabors, Louis B |
| بيانات النشر: |
BioMed Central Ltd. |
| سنة النشر: |
2012 |
| المجموعة: |
BioMed Central |
| مصطلحات موضوعية: |
Angiosarcoma, Primary Central Nervous System (CNS) Tumors, Sarcoma, Bevacizumab, Temozolomide |
| الوصف: |
Introduction Primary angiosarcoma of the brain is extremely rare; only 15 cases have been reported in adults over the last 25 years. Case presentations We describe two cases of primary angiosarcoma of the brain that are well characterized by imaging, histopathology, and immunohistochemistry. Case 1: our first patient was a 35-year-old woman who developed exophthalmos. Subtotal resection of a left extra-axial retro-orbital mass was performed. Case 2: our second patient was a 47-year-old man who presented to our facility with acute visual loss, word-finding difficulty and subtle memory loss. A heterogeneously-enhancing left sphenoid wing mass was removed. We also review the literature aiming at developing a rational approach to diagnosis and treatment, given the rarity of this entity. Conclusions Gross total resection is the standard of care for primary angiosarcoma of the brain. Adjuvant radiation and chemotherapy are playing increasingly recognized roles in the therapy of these rare tumors. |
| نوع الوثيقة: |
report |
| اللغة: |
English |
| العلاقة: |
http://www.jmedicalcasereports.com/content/6/1/251Test |
| الإتاحة: |
http://www.jmedicalcasereports.com/content/6/1/251Test |
| حقوق: |
Copyright 2012 Hackney et al.; licensee BioMed Central Ltd. |
| رقم الانضمام: |
edsbas.1C795AB8 |
| قاعدة البيانات: |
BASE |
