التفاصيل البيبلوغرافية
| العنوان: |
The potential impact of primary headache disorders on stroke risk |
| المؤلفون: |
Tsai, Chia-Lin, Chou, Chung-Hsing, Lee, Pei-Jung, Yin, Jiu-Haw, Chen, Shao-Yuan, Lin, Chun-Chieh, Sung, Yueh-Feng, Yang, Fu-Chi, Chung, Chi-Hsiang, Chien, Wu-Chien, Tsai, Chia-Kuang, Lee, Jiunn-Tay |
| بيانات النشر: |
BioMed Central Ltd. |
| سنة النشر: |
2016 |
| المجموعة: |
BioMed Central |
| مصطلحات موضوعية: |
Tension-type headache, Migraine, Non-migrainous headache, Ischaemic stroke, Risk factor |
| الوصف: |
Background Headache such as migraine is associated with stroke. Studies focused on primary headache disorders (PHDs) as a risk factor for stroke are limited. The purpose of this population-based cohort study was to explore whether patients with PHDs were at a high risk for developing stroke. Methods A total of 1346 patients with PHDs were enrolled and compared with 5384 age-, gender- and co-morbidity-matched control cohorts. International Classification of Diseases, Clinical Modification codes were administered for the definition of PHDs, stroke, and stroke risk factors. Cox proportional-hazards regressions were performed for investigating hazard ratios (HR). Results PHDs patients exhibited a 1.49 times (95% CI :1.15–1.98, p < 0.01) higher risk for developing ischaemic stroke compared with that of control cohorts. Both migraine (HR = 1.22, 95% CI :1.13–1.97, p < 0.05) and tension-type headache (HR = 2.29, 95% CI :1.22–2.80, p < 0.01) were associated with an increased risk of ischemic stroke. Females with PHDs were at greater risk of developing ischaemic stroke (HR = 1.49, 95% CI :1.13–1.90, p < 0.01) than those without PHDs. PHDs patient aged 45 to 64 years displayed significantly higher risk to develop ischaemic stroke (HR = 1.50, 95% CI: 1.11–2.10, p < 0.05) than the matched controls. The impact of PHDs on ischaemic stroke risk became gradually apparent by different following time intervals beyond 2 years after first diagnosis. Conclusion PHDs is suggestive of an incremental risk for ischaemic stroke with gender-dependent, age-specific and time-dependent characteristics. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| العلاقة: |
http://www.thejournalofheadacheandpain.com/content/17/1/108Test |
| الإتاحة: |
http://www.thejournalofheadacheandpain.com/content/17/1/108Test |
| حقوق: |
Copyright 2016 The Author(s). |
| رقم الانضمام: |
edsbas.1736C09F |
| قاعدة البيانات: |
BASE |
