التفاصيل البيبلوغرافية
| العنوان: |
Effect of hourly concentration of particulate matter on peak expiratory flow in hospitalized children: a panel study. |
| المؤلفون: |
Yamazaki, Shin, Shima, Masayuki, Ando, Michiko, Nitta, Hiroshi, Watanabe, Hiroko, Nishimuta, Toshiyuki |
| المساهمون: |
山崎, 新, 80391168 |
| بيانات النشر: |
BioMed Central Ltd. |
| سنة النشر: |
2011 |
| المجموعة: |
Kyoto University Research Information Repository (KURENAI) / 京都大学学術情報リポジトリ |
| مصطلحات موضوعية: |
Adolescent, Air Pollutants/toxicity, Asthma/physiopathology, Child, Environmental Monitoring, Female, Humans, Inhalation Exposure, Japan, Male, Particulate Matter/toxicity, Peak Expiratory Flow Rate/drug effects, Spirometry/instrumentation |
| الوصف: |
[Background]Little information is available on the possible association between hourly short-term air pollution and peak expiratory flow (PEF) in asthmatic children. [Methods]PEF was measured twice daily, from October through December, 2000, in 17 children aged 8 to 15 years hospitalized with severe asthma. A total of 1198 PEF measurements were made at 7 a.m. and 1175 at 7 p.m. Measurements were conducted immediately prior to medication under the guidance of trained nurses. PEF changes were estimated in 10-μg/m3 increments of particulate matter with a 50% cut-off aerodynamic diameter of ≤2.5 μm (PM2.5), with adjustment for sex, age, height, and temperature. Lagged-hour exposures of up to 24 hours were examined. [Results]Increased 24-hour mean concentration of PM2.5 was associated with a decrease in both morning and evening PEF (-3.0 l/minute; 95%CI: -4.6, -1.4 and -4.4 l/minute; 95%CI: -7.1, -1.7, respectively). In addition, hourly concentrations of PM2.5 and PEF showed a significant association between some lags of PM2.5 and PEF. Effect size was almost -3 l/minute in both morning and evening PEF for an hourly PM2.5 concentration of 10 μg/m3 in several lags. Even after adjustment for other air pollutants, some of the significant associations with PEF remained. [Conclusion]Among hospitalized children with severe asthma, increased hourly concentration of PM2.5 was associated with a decrease in PEF. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| تدمد: |
1476-069X |
| العلاقة: |
http://hdl.handle.net/2433/159712Test; AA1205076X; Environmental health : a global access science source; 10; 15 |
| الإتاحة: |
http://hdl.handle.net/2433/159712Test |
| حقوق: |
© 2011 Yamazaki et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0Test), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| رقم الانضمام: |
edsbas.472EDB09 |
| قاعدة البيانات: |
BASE |
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