Regulation of antimicrobial activity and xenocoumacins biosynthesis by pH in Xenorhabdus nematophila
| العنوان: | Regulation of antimicrobial activity and xenocoumacins biosynthesis by pH in Xenorhabdus nematophila |
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| المؤلفون: | Jiangtao Gao, Shujing Zhang, Muhammad Bilal, Xing Zhang, Yonghong Wang, Shuqi Guo, Xiangling Fang, Qi Liu |
| المصدر: | Microbial Cell Factories Microbial Cell Factories, Vol 16, Iss 1, Pp 1-14 (2017) |
| بيانات النشر: | BioMed Central, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0301 basic medicine, Indoles, 030106 microbiology, lcsh:QR1-502, Bioengineering, Xenocoumacin 2, Xenorhabdus nematophila YL001, Biology, Antimicrobial activity, medicine.disease_cause, Applied Microbiology and Biotechnology, lcsh:Microbiology, Xenorhabdus, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Bacterial Proteins, Photorhabdus luminescens, medicine, Benzopyrans, Xenorhabdus nematophila, pH, Research, Pathogenic bacteria, Hydrogen-Ion Concentration, biology.organism_classification, Antibiotic production, Antimicrobial, Anti-Bacterial Agents, Culture Media, 030104 developmental biology, chemistry, Biological control, Fermentation, Bacteria, Biotechnology |
| الوصف: | Background Xenocoumacin 1 (Xcn1) and Xenocoumacin 2 (Xcn2) are the main antimicrobial compounds produced by Xenorhabdus nematophila. Culture conditions, including pH, had remarkably distinct effects on the antimicrobial activity of X. nematophila. However, the regulatory mechanism of pH on the antimicrobial activity and antibiotic production of this bacterium is still lacking. Results With the increase of initial pH, the antimicrobial activity of X. nematophila YL001 was improved. The levels of Xcn1 and nematophin at pH 8.5 were significantly (P |
| اللغة: | English |
| تدمد: | 1475-2859 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fc1d36700e444188888735b911f10bTest http://europepmc.org/articles/PMC5688692Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b6fc1d36700e444188888735b911f10b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14752859 |
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