دورية أكاديمية
Clinical course and challenging management of early COVID-19 infection after heart transplantation: case report of two patients
| العنوان: | Clinical course and challenging management of early COVID-19 infection after heart transplantation: case report of two patients |
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| المؤلفون: | TCHANA-SATO, Vincent, ANCION, Arnaud, TRIDETTI, Julien, Sakalihasan, Natzi, Hayette, Marie-Pierre, Detry, Olivier, Delvenne, Philippe, AMABILI, Philippe, Senard, Marc, HOUGRAND, Olivier, SZECEL, Delphine, LAVIGNE, Jean-Paul, Minga Lowampa, Elie, Ponte, Charlotte, MAQUOI, Isabelle, Morimont, Philippe, VAN DEN BULCK, Mélissa, DELBOUILLE, Marie-Hélène, Defraigne, Jean-Olivier, Lancellotti, Patrizio |
| المصدر: | BMC Infectious Diseases (2021-01) |
| بيانات النشر: | BioMed Central |
| سنة النشر: | 2021 |
| المجموعة: | University of Liège: ORBi (Open Repository and Bibliography) |
| مصطلحات موضوعية: | severe acute respiratory syndrome coronavirus 2, Coronavirus disease 2019, heart transplantation, Life sciences, Microbiology, Sciences du vivant, Microbiologie |
| الوصف: | peer reviewed ; Background: There are limited data on Coronavirus disease 2019 (COVID-19) in solid organ transplant patients, especially in heart transplant recipients, with only a few case reports and case series described so far. Heart transplant recipients may be at particular high risk due to their comorbidities and immunosuppressed state. Case presentation: This report describes the clinical course and the challenging management of early COVID-19infection in two heart transplant recipients who tested positive for the SARS-CoV-2 virus in the perioperative period of the transplant procedure. The two patients developed a severe form of the disease and ultimately died despite the initiation of an antiviral monotherapy with hydroxychloroquine coupled with the interruption of mycophenolate mofetil. Conclusions: These two cases illustrate the severity and poor prognosis of COVID-19 in the perioperative period of a heart transplant. Thorough screening of donors and recipients is mandatory, and the issue of asymptomatic carriers needs to be addressed. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1471-2334 |
| العلاقة: | urn:issn:1471-2334; https://orbi.uliege.be/handle/2268/257630Test; info:hdl:2268/257630; https://orbi.uliege.be/bitstream/2268/257630/1/Tchana-Sato_et_al-2021-BMC_Infectious_Diseases%20%281%29.pdfTest; scopus-id:2-s2.0-85099659212; info:pmid:33472599 |
| DOI: | 10.1186/s12879-021-05793-6 |
| الإتاحة: | https://doi.org/10.1186/s12879-021-05793-6Test https://orbi.uliege.be/handle/2268/257630Test https://orbi.uliege.be/bitstream/2268/257630/1/Tchana-Sato_et_al-2021-BMC_Infectious_Diseases%20%281%29.pdfTest |
| حقوق: | open access ; http://purl.org/coar/access_right/c_abf2Test ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.97D2EF34 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 14712334 |
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| DOI: | 10.1186/s12879-021-05793-6 |