التفاصيل البيبلوغرافية
| العنوان: |
Lactic acid bacteria reduce bacterial diarrhea in rabbits via enhancing immune function and restoring intestinal microbiota homeostasis. |
| المؤلفون: |
Li, Huimin, Leng, Chaoliang, Chen, Nan, Ding, Qinchao, Yuan, Yizhao, Zheng, Yilei, Zhu, Ge, Chen, Chen, Xu, Lichang, Shuai, Jiangbing, Jiang, Qinting, Ren, Daxi, Wang, Huanan |
| المصدر: |
BMC Veterinary Research; 4/20/2024, Vol. 20 Issue 1, p1-12, 12p |
| مصطلحات موضوعية: |
LACTIC acid bacteria, GUT microbiome, ENTEROCOCCUS faecium, SHORT-chain fatty acids, PROBIOTICS, HOMEOSTASIS |
| مستخلص: |
Background: Numerous previous reports have demonstrated the efficacy of Lactic acid bacteria (LAB) in promoting growth and preventing disease in animals. In this study, Enterococcus faecium ZJUIDS-R1 and Ligilactobaciiius animalis ZJUIDS-R2 were isolated from the feces of healthy rabbits, and both strains showed good probiotic properties in vitro. Two strains (108CFU/ml/kg/day) were fed to weaned rabbits for 21 days, after which specific bacterial infection was induced to investigate the effects of the strains on bacterial diarrhea in the rabbits. Results: Our data showed that Enterococcus faecium ZJUIDS-R1 and Ligilactobaciiius animalis ZJUIDS-R2 interventions reduced the incidence of diarrhea and systemic inflammatory response, alleviated intestinal damage and increased antibody levels in animals. In addition, Enterococcus faecium ZJUIDS-R1 restored the flora abundance of Ruminococcaceae1. Ligilactobaciiius animalis ZJUIDS-R2 up-regulated the flora abundance of Adlercreutzia and Candidatus Saccharimonas. Both down-regulated the flora abundance of Shuttleworthia and Barnesiella to restore intestinal flora balance, thereby increasing intestinal short-chain fatty acid content. Conclusions: These findings suggest that Enterococcus faecium ZJUIDS-R1 and Ligilactobaciiius animalis ZJUIDS-R2 were able to improve intestinal immunity, produce organic acids and regulate the balance of intestinal flora to enhance disease resistance and alleviate diarrhea-related diseases in weanling rabbits. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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