Clinical relevance and biology of circulating tumor cells
| العنوان: | Clinical relevance and biology of circulating tumor cells |
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| المؤلفون: | Klaus Pantel, Natalia Bednarz-Knoll, Catherine Alix-Panabières |
| المصدر: | Breast Cancer Research : BCR |
| بيانات النشر: | BioMed Central, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | CA15-3, Oncology, medicine.medical_specialty, business.industry, Cancer, Breast Neoplasms, Review, medicine.disease, Neoplastic Cells, Circulating, Prognosis, Peripheral blood, medicine.anatomical_structure, Breast cancer, Circulating tumor cell, Surgical oncology, Internal medicine, medicine, Animals, Humans, Clinical significance, Female, Bone marrow, business, Neoplasm Staging |
| الوصف: | Most breast cancer patients die due to metastases, and the early onset of this multistep process is usually missed by current tumor staging modalities. Therefore, ultrasensitive techniques have been developed to enable the enrichment, detection, isolation and characterization of disseminated tumor cells in bone marrow and circulating tumor cells in the peripheral blood of cancer patients. There is increasing evidence that the presence of these cells is associated with an unfavorable prognosis related to metastatic progression in the bone and other organs. This review focuses on investigations regarding the biology and clinical relevance of circulating tumor cells in breast cancer. |
| اللغة: | English |
| تدمد: | 1465-542X 1465-5411 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e0ce48f8f0a4e44fd4aad6504e3a45Test http://europepmc.org/articles/PMC3326546Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....83e0ce48f8f0a4e44fd4aad6504e3a45 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1465542X 14655411 |
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