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Inflammatory status affects the antitumor activity of poly-epitope-peptide vaccination against the thymidylate synthase in metastatic colo-rectal cancer patients enrolled in TSPP/VAC-1 Phase Ib trial

التفاصيل البيبلوغرافية
العنوان: Inflammatory status affects the antitumor activity of poly-epitope-peptide vaccination against the thymidylate synthase in metastatic colo-rectal cancer patients enrolled in TSPP/VAC-1 Phase Ib trial
المؤلفون: Maria Grazia Rossetti, Cirino Botta, Tatiana Cosima Baldari, Pierpaolo Pastina, Francesco Salvatore Carbone, Valerio Nardone, Cristina Ulivieri, Pierpaolo Correale, Claudia Gandolfo, Elodia Claudia Martino, Maria Grazia Cusi, Antonella Fioravanti, Luigi Pirtoli, Pierosandro Tagliaferri
المصدر: Journal for Immunotherapy of Cancer
بيانات النشر: BioMed Central, 2015.
سنة النشر: 2015
مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Antitumor activity, Cancer Research, biology, business.industry, Immunology, DNA replication, Peptide, Colo-rectal cancer, Bioinformatics, Thymidylate synthase, Epitope, Vaccination, Oncology, chemistry, Poster Presentation, Peptide vaccine, Cancer research, biology.protein, Molecular Medicine, Immunology and Allergy, Medicine, business
الوصف: Meeting abstracts Thymidylate synthase (TS) is a tumor-associated-enzyme crucial for DNA replication and inhibited by 5′-fluorouracil. TSPP is a previously characterized anticancer poly-epitope peptide vaccine to TS ( Correale P, JNCI 2005 97:1437 ). TSPP/VAC-1 is a three-arm dose-finding Phase
اللغة: English
تدمد: 2051-1426
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac091dd198771eecc466d66f47e74d8aTest
http://europepmc.org/articles/PMC4652525Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....ac091dd198771eecc466d66f47e74d8a
قاعدة البيانات: OpenAIRE
الوصف
تدمد:20511426