نتائج البحث

1

A bispecific CAR-T cell therapy targeting BCMA and CD38 in relapsed or refractory multiple myeloma

المؤلفون: Huiwen Jiang, Ping Yin, Haiming Kou, Dan Jin, Chunyan Sun, Zhihui Wang, Zhiping Huang, Yu Hu, Lisha Ai, Li Cai, Xinying Zhao, Gaoquan Hua, Chenggong Li, Linghui Xia, Heng Mei, Lei Chen, Jun Deng, Tao Guo, Lin Liu, Lu Tang, Yimeng Xia, Sha Ke

المصدر: Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-17 (2021)

مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Chimeric antigen receptor-T cells, medicine.medical_treatment, Neutropenia, CD38, Immunotherapy, Adoptive, Mice, Antigen, Multiple myeloma, Internal medicine, Cell Line, Tumor, Medicine, Animals, Humans, Diseases of the blood and blood-forming organs, B-Cell Maturation Antigen, Molecular Biology, RC254-282, Aged, Hematology, Leukopenia, Receptors, Chimeric Antigen, business.industry, Research, Bispecific CAR, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunotherapy, Middle Aged, medicine.disease, ADP-ribosyl Cyclase 1, BCMA, Molecular Docking Simulation, Cytokine release syndrome, Female, medicine.symptom, RC633-647.5, Neoplasm Recurrence, Local, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8addea709c52c74756db94509d2a8095Test
http://europepmc.org/articles/PMC8501733Test

2

T cell exhaustion is associated with the risk of papillary thyroid carcinoma and can be a predictive and sensitive biomarker for diagnosis

المؤلفون: Qi Chen, Yingjie Dai, Yuechu Dai, Hui Zhang, Yanyun Ruan, Tianjun Jia, Chumeng Zhu, Hongsheng Lu, Yong Zhou, Lilong Fan

المصدر: Diagnostic Pathology
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, Histology, endocrine system diseases, Lymphocyte, T cell, Programmed Cell Death 1 Receptor, Hashimoto Disease, Lymphocyte Activation, Thyroiditis, B7-H1 Antigen, Pathology and Forensic Medicine, Malignant transformation, Thyroid carcinoma, Young Adult, Lymphocytes, Tumor-Infiltrating, T-Lymphocyte Subsets, PD-1, medicine, Tumor Microenvironment, Humans, RB1-214, Thyroid Neoplasms, Aged, Cell Proliferation, Aged, 80 and over, Lymph node metastasis, Chemistry, Research, Thyroid, General Medicine, Hashimoto’s thyroiditis, Biomarker, Middle Aged, medicine.disease, medicine.anatomical_structure, Phenotype, Thyroid Cancer, Papillary, Case-Control Studies, Papillary thyroid carcinoma, Cancer research, Immunohistochemistry, Female, Nodular goiter, CD8, Goiter, Nodular

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2673d241662c30669ffb0286f82acc19Test
http://europepmc.org/articles/PMC8408957Test

3

Questioning the IGF1 receptor’s assigned role in CRC – a case for rehabilitation?

المؤلفون: Hans-Michael Behrens, Stefan Schreiber, Christoph Röcken, Steffen M. Heckl, Marie Pellinghaus, Sandra Krüger

المصدر: BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Cytoplasm, Cancer therapy, DNA Repair, Genotyping Techniques, Colorectal cancer, Receptor, IGF Type 1, 0302 clinical medicine, Surgical oncology, Medicine, IGF1 receptor, Aged, 80 and over, biology, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Immunohistochemistry, Neoplasm Proteins, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Colonic Neoplasms, Female, Colorectal Neoplasms, Research Article, Cancer risk factor, Adult, medicine.medical_specialty, lcsh:RC254-282, 03 medical and health sciences, Internal medicine, Genetics, Lymphatic vessel, Humans, Grading (tumors), Insulin-like growth factor 1 receptor, Aged, Cancer prognosis, business.industry, Membrane Proteins, medicine.disease, Survival Analysis, Receptor, Insulin, body regions, Insulin receptor, 030104 developmental biology, Genes, ras, Tissue Array Analysis, biology.protein, business, Immunostaining

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5623eb019612c73db62054ed1064fefTest
http://europepmc.org/articles/PMC7391533Test

4

GLUT-1 as a predictor of worse prognosis in pancreatic adenocarcinoma: immunohistochemistry study showing the correlation between expression and survival

المؤلفون: Carlos Gordillo, Magdalena Adrados, Maria del Mar Achalandabaso Boira, Marcello Di Martino, Elena Martín-Pérez

المصدر: BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Population, lcsh:RC254-282, Gastroenterology, Cohort Studies, symbols.namesake, Surgical oncology, Pancreatic cancer, Internal medicine, Genetics, medicine, Biomarkers, Tumor, Humans, education, Fisher's exact test, Antibody, Aged, Retrospective Studies, Aged, 80 and over, education.field_of_study, Glucose Transporter Type 1, Prognostic factor, business.industry, GLUT-1, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Prognosis, Immunohistochemistry, Survival Analysis, Pancreatic Neoplasms, Oncology, Cohort, symbols, Mann–Whitney U test, Adenocarcinoma, Female, business, Student's t-test, Carcinoma, Pancreatic Ductal, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6d81efa96625918d92869ce7169c6eTest
http://europepmc.org/articles/PMC7510075Test

5

TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with Rac1

المؤلفون: Yihua Pang, Daoxin Ma, Jingjing Ye, Yanan Zhao, Xinlu Wang, Fei Lu, Yan Wang, Chunyan Ji, Tao Sun, Min Ji, Jingxin Li, Peng Li, Na Liu, Ruiqing Wang

المصدر: Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-18 (2020)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, rac1 GTP-Binding Protein, Cancer Research, TNFAIP8, Apoptosis, Mice, 0302 clinical medicine, AML, Cell Movement, Transcriptional regulation, Tumor Cells, Cultured, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Kinase, ETS transcription factor family, Myeloid leukemia, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Gene Expression Regulation, Neoplastic, Leukemia, ERK, Leukemia, Myeloid, Acute, Oncology, 030220 oncology & carcinogenesis, Female, Chemoresistance, Rac1, Signal Transduction, Adult, Adolescent, RAC1, Antineoplastic Agents, Biology, lcsh:RC254-282, 03 medical and health sciences, Young Adult, medicine, Biomarkers, Tumor, Animals, Humans, Aged, Cell Proliferation, Research, medicine.disease, Xenograft Model Antitumor Assays, Mice, Inbred C57BL, 030104 developmental biology, Drug Resistance, Neoplasm, Case-Control Studies, Cancer research, Apoptosis Regulatory Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4619bbfcf171dbdd36a9caa514ae5c7Test
http://europepmc.org/articles/PMC7427779Test

6

PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α

المؤلفون: Minle Li, Hongmei Yong, Jin Bai, Pingfu Hou, Yan-Su Chen, Tao Jiang, Jun Song, Tian Lin, Fang Chen, Junnian Zheng, Yu Pan, Jingjing Li

المصدر: Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Colorectal cancer, PTBP3, Kaplan-Meier Estimate, Metastasis, 0302 clinical medicine, Cell Movement, Genes, Reporter, Neoplasm Metastasis, Tissue microarray, Protein translation, Neovascularization, Pathologic, Cell migration, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, Polypyrimidine Tract-Binding Protein, Adult, HIF-1α, Biology, lcsh:RC254-282, Models, Biological, 03 medical and health sciences, In vivo, Cell Line, Tumor, medicine, Humans, Aged, Cell Proliferation, Neoplasm Staging, Messenger RNA, Oncogene, Research, medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, Internal ribosome entry site, 030104 developmental biology, Protein Biosynthesis, Cancer research, Y-Box-Binding Protein 1, Neoplasm Grading, Tumor metastasis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b67ac2a09cd500afd63119ddeb0233Test
http://europepmc.org/articles/PMC6622005Test

7

HTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions

المؤلفون: Hossein Rahimi, Hanieh Tarokhian, Mohammad Mehdi Akbarin, Alireza Bari, Houshang Rafatpanah, Abbas Shirdel, Seyed Abdolrahim Rezaee, Arman Mosavat, Samaneh Ramezani

المصدر: BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Retroviridae Proteins, HTLV-1-proviral load, 0302 clinical medicine, HBZ, RAR-related orphan receptor gamma, immune system diseases, hemic and lymphatic diseases, Tropical spastic paraparesis, Medicine, Leukemia-Lymphoma, Adult T-Cell, Human T-lymphotropic virus 1, FOXP3, virus diseases, Forkhead Transcription Factors, Middle Aged, Nuclear Receptor Subfamily 1, Group F, Member 3, Viral Load, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Paraparesis, Tropical Spastic, Gene Expression Regulation, Neoplastic, Leukemia, Basic-Leucine Zipper Transcription Factors, Oncology, 030220 oncology & carcinogenesis, Host-Pathogen Interactions, Female, bcl-Associated Death Protein, RORγt, Research Article, Adult, Gene Expression Regulation, Viral, Peripheral blood mononuclear cell, lcsh:RC254-282, Virus, Adult T-cell leukemia/lymphoma, 03 medical and health sciences, IFNλ3, Genetics, BAD, Humans, RNA, Messenger, AKT1, business.industry, Th1 Cells, medicine.disease, HTLV-I Infections, Lymphoma, 030104 developmental biology, Immunology, Leukocytes, Mononuclear, Rad51 Recombinase, business, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d1658deba2d4b58605e3a6a272b8eeTest
http://europepmc.org/articles/PMC6303995Test

8

CX3CL1/CX3CR1 axis attenuates early brain injury via promoting the delivery of exosomal microRNA-124 from neuron to microglia after subarachnoid hemorrhage

المؤلفون: Xiang Li, Xiao Chen, Haitao Shen, Gang Chen, Yang Wang, Yunhai Zhang, Haiying Li, Ming Jiang, Jiang Wu, Zhengquan Yu

المصدر: Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)

مصطلحات موضوعية: Adult, Male, MicroRNA-124, Immunology, Central nervous system, CX3C Chemokine Receptor 1, Exosomes, Exosome, lcsh:RC346-429, CX3CL1, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, CX3CR1, Neuroinflammation, microRNA, medicine, Animals, Humans, Subarachnoid hemorrhage, cardiovascular diseases, lcsh:Neurology. Diseases of the nervous system, Cells, Cultured, Aged, Aged, 80 and over, Neurons, Microglia, business.industry, Chemokine CX3CL1, General Neuroscience, Research, Gene Transfer Techniques, Middle Aged, nervous system diseases, Rats, MicroRNAs, medicine.anatomical_structure, Neurology, Brain Injuries, Cancer research, Female, Neuron, business, Early brain injury

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2963255595b4854146c941558083eb94Test
http://europepmc.org/articles/PMC7362528Test

9

The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3

المؤلفون: Yasufumi Kijima, Tomotake Kanai, Hiroyuki Kawashima, Go Okumura, Naoki Kondo, Naoto Endo, Akira Ogose, Masayasu Okada, Hiroshige Sano

المصدر: Journal of Orthopaedic Surgery and Research
Journal of Orthopaedic Surgery and Research, Vol 15, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: 0301 basic medicine, Adult, lcsh:Diseases of the musculoskeletal system, Cell Survival, MAP Kinase Signaling System, Matrix metalloproteinase, Antioxidants, JNK pathway, Arthritis, Rheumatoid, 03 medical and health sciences, 0302 clinical medicine, Sequestosome 1, Drug Delivery Systems, lcsh:Orthopedic surgery, RA-FLS, medicine, Humans, Orthopedics and Sports Medicine, education, Cells, Cultured, chemistry.chemical_classification, Aged, 80 and over, education.field_of_study, Reactive oxygen species, MMP-3, Kinase, business.industry, Low-dose NAC, Proteolytic enzymes, Middle Aged, medicine.disease, Synoviocytes, Acetylcysteine, lcsh:RD701-811, 030104 developmental biology, Treatment Outcome, chemistry, 030220 oncology & carcinogenesis, Rheumatoid arthritis, Cancer research, Phosphorylation, MH7A, Surgery, Tumor necrosis factor alpha, Female, Matrix Metalloproteinase 3, lcsh:RC925-935, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77be56a7f3c794c1fc591233de09d1ddTest
http://europepmc.org/articles/PMC7371465Test

10

A case of Turcot’s syndrome type 1 with loss of immunoexpression of MSH6 in colon cancer and liver metastasis due to secondary somatic mutation in coding mononucleotide (C)8 tract: a case report

المؤلفون: Yosuke Shimizu, Hirofumi Tazawa, Takao Hinoi, Shintaro Akabane, Takeshi Sudo, Hideki Yamamoto, Haruna Kubota, Toshihiro Misumi, Naoto Hadano, Takashi Onoe, Takahisa Suzuki, Daiki Taniyama, Kazuya Kuraoka, Kiwamu Akagi, Wataru Shimizu, Masato Kojima, Kohei Ishiyama, Haruki Sada, Hirotaka Tashiro

المصدر: BMC Medical Genetics
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-7 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Case Report, DNA Mismatch Repair, Metastasis, 0302 clinical medicine, PMS2, Genetics (clinical), Brain Neoplasms, Liver Neoplasms, Middle Aged, Lynch syndrome, Pedigree, DNA-Binding Proteins, medicine.anatomical_structure, Mismatch repair gene, 030220 oncology & carcinogenesis, Colonic Neoplasms, Adenocarcinoma, Female, Colorectal Neoplasms, Adult, lcsh:Internal medicine, congenital, hereditary, and neonatal diseases and abnormalities, lcsh:QH426-470, MLH1, Descending colon, Frameshift mutation, 03 medical and health sciences, Neoplastic Syndromes, Hereditary, Genetics, medicine, Humans, Genetic Predisposition to Disease, lcsh:RC31-1245, Turcot’s syndrome type 1, Base Sequence, business.industry, Somatic mutation, nutritional and metabolic diseases, Cancer, medicine.disease, digestive system diseases, lcsh:Genetics, 030104 developmental biology, Mutation, Cancer research, Microsatellite instability, business, Microsatellite Repeats

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338da9bc7b140d1695c5d7ac724c0369Test
http://europepmc.org/articles/PMC7345515Test

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