التفاصيل البيبلوغرافية
العنوان:
The role of nailfold capillaroscopy in interstitial lung diseases - can it differentiate idiopathic cases from collagen tissue disease associated interstitial lung diseases?
المؤلفون:
Çobankara , Balkarlı A , Özgür Önal , Altınışık G , Çakmakçı Karadoğan D
المصدر:
Tuberkuloz ve Toraks . 63:22-30
بيانات النشر:
Bilimsel Tip Publishing House, 2015.
سنة النشر:
2015
مصطلحات موضوعية:
rheumatoid arthritis , Male , Pathology , Exacerbation , very elderly , capillaroscopy , Critical Care and Intensive Care Medicine , capillary , Microscopic Angioscopy , Idiopathic pulmonary fibrosis , collagen disease , Usual interstitial pneumonia , differential diagnosis , middle aged , interstitial lung disease , interstitial pneumonia , Aged, 80 and over , clinical article , Interstitial lung disease , respiratory system , female , medicine.anatomical_structure , Rheumatoid arthritis , lung diffusion capacity , Adult , Pulmonary and Respiratory Medicine , medicine.medical_specialty , Interstitial lung diseases , behavioral disciplines and activities , Article , Kulak, Burun, Boğaz , Solunum Sistemi , lung , Diagnosis, Differential , vascularization , image analysis , medicine , Humans , controlled study , human , angioscopy , nail , Aged , Collagen disease , Lung , business.industry , Collagen Diseases , capillary density , medicine.disease , oxygen saturation , Idiopathic Pulmonary Fibrosis , Capillaries , respiratory tract diseases , body regions , fibrosing alveolitis , Nails , Nailfold capillaroscopy , pathology , Surgery , Differential diagnosis , Lung Diseases, Interstitial , business , Sjoegren syndrome
الوصف:
Introduction: Nailfold capillaroscopy (NFC) is a non-invasive diagnostic test that is mostly used for early diagnosis of collagen tissue diseases (CTDs). We aimed to evaluate whether NFC findings could be a clue for discriminating idiopathic interstitial lung diseases (ILD) from CTD associated ILDs (CTD-ILD). Additionally it was aimed to determine whether NFC could be helpful in discriminating usual interstitial pneumonia (UIP) pattern from non-specific interstitial pneumonia (NSIP) pattern. Materials and Methods: We grouped patients into three main groups: 15 CTD-ILD, 18 idiopathic ILD, and 17 patients in the control group. The CTD-ILD group was split into two subgroups: 8 patients with Sjögren’s syndrome (SJS)-associated ILD and 7 with rheumatoid arthritis (RA)-associated ILD. The idiopathic-ILD group consisted of 10 idiopathic NSIP and 8 IPF patients. The control group consisted of 10 SJS and 7 RA patients without lung disease. None of the patients were on acute exacerbation at the time of examination, and none had Reynaud’s phenomenon. Results: Mean capillary density was significantly reduced only in the CTD-ILD group as compared to the control group (p= 0.006). In subgroup analysis, it was determined that RA-ILD, IPF, and SJSILD subgroups had more severe capillaroscopic abnormalities. Mean capillary density in patients with the UIP pattern was reduced compared to patients with the NSIP pattern and those in the control group; p values were 0.008 and < 0.001, respectively. Conclusion: This study is to be the first describing and comparing the nailfold capillaroscopic findings of patients with NSIP and UIP patterns. NFC findings can be helpful in discriminating UIP patterns from NSIP patterns. But to show its role in differentiating idiopathic disease, more studies with more patients are needed. © 2015, Ankara University. All rights reserved.
وصف الملف:
application/pdf
تدمد:
0494-1373
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194c1e5880a9985309857799c660334aTest https://doi.org/10.5578/tt.8673Test
حقوق:
OPEN
رقم الانضمام:
edsair.doi.dedup.....194c1e5880a9985309857799c660334a
قاعدة البيانات:
OpenAIRE
