دورية أكاديمية
Gut microbiome and thyroid autoimmunity
| العنوان: | Gut microbiome and thyroid autoimmunity |
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| المؤلفون: | Virili C., Stramazzo I., Centanni M. |
| المساهمون: | Virili, C., Stramazzo, I., Centanni, M. |
| بيانات النشر: | Bailliere Tindall Ltd THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND |
| سنة النشر: | 2021 |
| المجموعة: | Sapienza Università di Roma: CINECA IRIS |
| مصطلحات موضوعية: | Graves' orbithopathy, Graves’ disease, gut microbiota, Hashimoto's thyroiditi, hypothyroidism, thyroxine malabsorption |
| الوصف: | Intestinal microbiota gained attention due to its pleiotropic effect on intestinal barrier, nutrients metabolism and on immune system development and functions. Recent evidence pointed out a possible role of an altered gut microbiota composition in the pathogenesis and progression of several autoimmune disorders, occurring at gastrointestinal level or far apart. In thyroid autoimmune disorders, encompassing Hashimoto's thyroiditis, Graves’ disease and thyroid-associated orbitopathy, the combined effect of environmental triggers and genetic predisposing background, lead to the loss of self-tolerance and to auto-aggressive damage, involving both cellular and humoral networks of immune system. This review is aimed at assessing the current knowledge about the studies published on the fecal microbiota composition in patients bearing thyroid autoimmune diseases. We further examined the reciprocal interaction between gut microbiota composition and the most used treatments for thyroid disorders. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/33648848; info:eu-repo/semantics/altIdentifier/wos/WOS:000661250400001; volume:35; issue:3; numberofpages:15; journal:BAILLIERE'S BEST PRACTICE & RESEARCH. CLINICAL ENDOCRINOLOGY & METABOLISM; http://hdl.handle.net/11573/1555620Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85101702301 |
| DOI: | 10.1016/j.beem.2021.101506 |
| الإتاحة: | https://doi.org/10.1016/j.beem.2021.101506Test http://hdl.handle.net/11573/1555620Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.5BC433E1 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.beem.2021.101506 |
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