دورية أكاديمية
Analysis of the correlation between the systemic inflammatory response index and the severity of coronary vasculopathy
| العنوان: | Analysis of the correlation between the systemic inflammatory response index and the severity of coronary vasculopathy |
|---|---|
| المؤلفون: | Ting He, Yinhua Luo, Jingjing Wan, Ling Hou, Ke Su, Jinbo Zhao, Yuanhong Li |
| المصدر: | Biomolecules & Biomedicine (2024) |
| بيانات النشر: | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Biology (General) |
| مصطلحات موضوعية: | Systemic inflammatory response index, coronary heart disease, Gensini score, severity of coronary artery disease, Biology (General), QH301-705.5 |
| الوصف: | This study aims to analyze the correlation between Systemic Inflammatory Response Index (SIRI) and the severity of coronary artery stenosis in patients with coronary heart disease (CHD). It also aims to assess the predictive value of SIRI for the severity of coronary artery stenosis. A total of 2990 patients who underwent coronary angiography were included in this study. The Gensini score was used to estimate the severity of coronary vascular lesions. The predictive ability of SIRI for CHD was evaluated using receiver operating characteristic (ROC) curves. Binary multivariate logistic regression analysis was used to predict the likelihood of CHD based on the SIRI index. The results showed that people with higher SIRI index were more likely to have CHD (P < 0.001). After controlling for other risk factors, the highest quartile had a significantly higher incidence of coronary artery disease compared to the lowest quartile (odds ratio [OR] 2.25, 95% confidence interval [CI] 1.73-3.92, P < 0.001). Furthermore, the Gensini score was significantly higher in the fourth quartile group (T4) compared to the first (T1) and second (T2) quartile groups (P < 0.001). Additionally, the SIRI index was significantly higher in the group with severe coronary artery lesions compared to the mild and moderate groups (P < 0.001). The SIRI index also showed a higher predictive ability for the extent of coronary lesions under the ROC curve compared to other commonly used markers, including platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), and neutrophil-to-lymphocyte ratio (NLR) (P < 0.001). Therefore, SIRI index positively correlates with coronary artery stenosis in CHD patients, serving as an effective early screening marker for assessing stenosis severity. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2831-0896 2831-090X |
| العلاقة: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/10747Test; https://doaj.org/toc/2831-0896Test; https://doaj.org/toc/2831-090XTest |
| DOI: | 10.17305/bb.2024.10747 |
| الوصول الحر: | https://doaj.org/article/b14dce844e6943918ff7f633d56581baTest |
| رقم الانضمام: | edsdoj.b14dce844e6943918ff7f633d56581ba |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 28310896 2831090X |
|---|---|
| DOI: | 10.17305/bb.2024.10747 |