Bioengineering in Development of the Hybrid Artificial Pancreas
| العنوان: | Bioengineering in Development of the Hybrid Artificial Pancreas |
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| المؤلفون: | Clark K. Colton, E. S. Avgoustiniatos |
| المصدر: | Journal of Biomechanical Engineering. 113:152-170 |
| بيانات النشر: | ASME International, 1991. |
| سنة النشر: | 1991 |
| مصطلحات موضوعية: | Oxygen supply, Hybrid device, business.industry, Pancreatic tissue, medicine.medical_treatment, Biomedical Engineering, Biocompatible Materials, Capsules, Equipment Design, Infusion Pumps, Implantable, Diabetes mellitus therapy, Pancreas transplantation, Bioinformatics, Biocompatible material, Artificial pancreas, Insulin Infusion Systems, Physiology (medical), Diabetes Mellitus, Animals, Humans, Medicine, Pancreas Transplantation, business, Immune rejection |
| الوصف: | The hybrid artificial pancreas for treatment of diabetes consists of insulin-secreting pancreatic tissue which is surrounded by a membrane that protects the tissue from rejection by the immune system following implantation. In this paper, we review the alternative therapeutic approaches for diabetes under study and then discuss the technical requirements that must be met by a hybrid device useful to humans. Previous work on intravascular and extravascular immunoisolation devices is reviewed from the standpoint of these requirements, and three critical unresolved issues are discussed: biocompatibility, oxygen supply limitations, and prevention of immune rejection. |
| تدمد: | 1528-8951 0148-0731 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71279697580b40d12530b4ab64c8e1d0Test https://doi.org/10.1115/1.2891229Test |
| رقم الانضمام: | edsair.doi.dedup.....71279697580b40d12530b4ab64c8e1d0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15288951 01480731 |
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